Songuigama Coulibaly, Deto Ursul Jean-Paul N’guessan, Kouaho Avi kadjo Tanguy, Alain A. Kacou, Kpongbo Etienne Angora, Fabrice Koffi & Mahama Ouattara·Asian Journal of Chemical Sciences·2025
Aims: This pharmacochemical study aimed to design, synthesize, structurally characterize, and evaluate the anti-aspergillus activity of a new series of 6-chloroimidazo[1,2-a]pyridinyl–chalcone derivatives against an environmental strain of Aspergillus flavus, a major opportunisti...
Open access
Research Article10.9734/ajocs/2025/v15i6415
Songuigama Coulibaly, Jean-Paul D.U. N'guessan, Apleheni E.M. Adouko, Jean-Fabrice K. Koffi, Lise A Koffi & Mahama Ouattara·Chemical Science International Journal·2025
Carbapenems are a major class of antibiotics with a β-lactam nucleus that are distinguished by their effectiveness against many resistant pathogens. The discovery of Thienamycin, from Streptomyces cattleya, was the starting point for these antibiotics that revolutionized the trea...
Open access
Research Article10.9734/CSJI/2025/v34i1944
Songuigama Coulibaly, Jean-Paul D. U. N'guessan, Alain Kacou, Jean-Fabrice K. Koffi, Amelanh S. Diakité, Tanguy K. A. Kouaho & Mahama Ouattara·Chemical Science International Journal·2021
Antifungal therapeutics is confronted today with the challenge of drug resistance of most fungal germs to current antifungal drugs. Faced with this situation, the search for new and more efficient antifungal molecules that avoid the phenomenon of drug resistance becomes an urgent...
Open access
Research Article10.9734/CSJI/2021/v30i630235
Deto Ursul Jean-Paul N’guessan, Songuigama Coulibaly, Avi Tanguy Kouao, Alain A. Kacou, Kpongbo Etienne Angora, Fabrice Koffi, Ismaila Diallo & Mahama Ouattara·Chemical Science International Journal·2025
Background: Aspergillus fumigatus is the leading causative agent of invasive aspergillosis, a deadly opportunistic fungal infection in immunocompromised patients. The increasing emergence of azole-resistant strains necessitates the urgent development of new antifungal molecules....
Open access
Research Article10.9734/CSJI/2025/v34i61011
Deto Ursul Jean-Paul N’guessan, Songuigama Coulibaly, Alain A. Kacou, Kpongbo Etienne Angora, Fabrice Koffi & Mahama Ouattara·Asian Journal of Chemical Sciences·2025
Aims: The general objective assigned to this work was to contribute to the pharmacochemical development of new antifungal drugs derived from 6-Chloroimidazo [1,2-a]pyridine.This preliminary study was conducted on Candida parapsilosis, which is an increasingly difficult organism t...
Open access
Research Article10.9734/ajocs/2025/v15i3371
Background: To overcome drug resistance to current antimalarial drugs, we propose the synthesis and in vitro evaluation of the antiplasmodial activity of a series of 5-chlorobenzimidazolyl-chalcones against chloroquino sensitive (CQ-S) and chloroquino resistant (CQ-R) strains of...
Open access
Research Article10.9734/jpri/2021/v33i46B32925