Guillain-Barré syndrome (GBS) also known as acute demyelinating polyradiculoneuropathy (AIDP) is an immunologically mediated rare neurological disorder. The basic pathogenic mechanism is regulated by molecular mimicry. Usually there is a history of preceding infection which oc...
Open access
Research Article10.9734/jpri/2021/v33i53A33637
Background: Headache is common neurological problem experienced by ninety percent of the subjects globally. Prevalence of primary headache, mostly due to migraine, is ten to fifteen percent among the subjects worldwide and is the most disabling amongst the primary headache syndro...
Open access
Research Article10.9734/jpri/2021/v33i64B35321
Background: SARS-CoV-2 is a novel corona virus responsible for the dreadful COVID-19 pandemic. In more severely ill COVID-19 patients, clotting complications, such as microvascular thrombi in the arteries and veins, are also shown. Although uncommon in the entire population of C...
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Research Article10.9734/jpri/2021/v33i61A35464
The growing abundance of technology in the medical field has led to doctors' sensory de-skilling. Technology is seen replacing the clinical diagnosis based on sensory perception. Percussion as a skill has been lost from clinical practice. Though percussion disappeared from wards,...
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Research Article10.9734/jpri/2021/v33i60B34833
Coronavirus disease also (COVID 19) a worldwide pandemic contagious infection produced through the Coronavirus SAR.S-CoV2, and aberrant, overactive immunity and "chemokines" have been hypothesized as possible pathogenic reasons for rapid COVID 19 development. Because of a poor vi...
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Research Article10.9734/jpri/2021/v33i60B34734
Rodenticide is the term given for the compounds that are used in the killing of rats. The commonest compounds that are available as rodenticides are Aluminum phosphide, Zinc Phosphide, Yellow Phosphorus and Coumarins. Due to their easy availability in the general stores, these al...
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Research Article10.9734/jpri/2021/v33i54B33760
Background: Octreotide and terlipressin are two pharmacologic drugs used as an adjuvant therapy in the treatment of acute esophageal variceal bleeding. Large enough clinical trial data is not available, in comparing the efficacy of octreotide versus terlipressin as an adjunct to...
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Research Article10.9734/jpri/2021/v33i32B31748
Background: Metabolic syndrome is a syndrome of unified metabolic disorder which includes abdominal obesity (AO), hypertension, hypertriglyceridemia (HTG), hyperglycemia and decreased high-density lipoprotein (HDL). Metabolic syndrome subjects are exposed to greater chances to ha...
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Research Article10.9734/jpri/2021/v33i64A35316
Background: One of the clinical endpoints of atherosclerosis is stroke, the most prominent clinical manifestation of cerebrovascular disease. It is a cerebral blood vessel disease that nourishes the brain. A global health concern is stroke. It is the second most prevalent cause o...
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Research Article10.9734/jpri/2021/v33i64A35318
Endometrial cancer is one of the leading causes of death in post- menopausal women. It has significant impact on mortality and morbidity of women in the post-menopausal age group often requiring Hysterectomy along with Chemotherapy. Chemotherapy can be used to treat endometrial c...
Open access
Research Article10.9734/jpri/2021/v33i62B35168
Background: Malnutrition entails insufficiency arising of protein, vitamin, and trace elements related to inadequate and unstable diet which may cause poor quality of life and sometimes even lead to death. Undernourishment is the leading reason having a greater impact on outcomes...
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Research Article10.9734/jpri/2021/v33i62B35564
Background: Prediabetes is characterized by a long duration of insulin resistance and increased fasting plasma glucose. Among the various risk factors for cardiovascular atherosclerosis and prediabetes, insulin resistance is one of them. Glycemia has been recognized to affect mic...
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Research Article10.9734/jpri/2021/v33i63B35285
Muscle excisional is a very persistently complete and programmed idiosyncratic repetition, accomplished by many doctors all over the globe who treat sufferers presumed to be caused by the muscular disorder. Muscle excisional is vital in giving a particular reason for various neur...
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Research Article10.9734/jpri/2021/v33i63A35901
Background: Calculation of heart rate variability (HRV) is the most popular approach of actual evaluation of autonomic nervous system (ANS) dysregulation, representing natural physiological changes. The natural changes take place in the interim among successive heart beats when s...
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Research Article10.9734/jpri/2021/v33i60B34951
This study more on the role of trace elements such as iron(Fe), zinc(Zn), chromium(Cr), manganese(Mn), copper(Cu), cobalt(Co), selenium(sn) on the medicinal conditions like heart failure, myocardial infarction, cardiomyopathy, congestive heart failure, pericardial effusion, kesha...
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Research Article10.9734/jpri/2021/v33i60B34871
Scrub typhus is a zoonotic disease caused by Orientia tsutsugamushi. Scrub typhus presenting with thrombocytopenia has been reported up to half of patients with Scrub Typhus. Thrombocytopenia is usually complicated with multiorgan dysfunction and high mortality rate. Here we repo...
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Research Article10.9734/ijtdh/2021/v42i2130552
This article summarizes the literature related to the pathogenic mechanisms and treatment options for multiple sclerosis, an autoimmune, demyelinating disorder of the central nervous system. The etiology of MS is not known, both genetic and environmental factors are known to play...
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Research Article10.9734/jpri/2021/v33i60B34736
Blood sugar levels are elevated in diabetes mellitus (DM), the most prevalent metabolic disorder. Insulin deficiency or ineffectiveness is the primary cause of hyperglycemia, affecting carbs and protein, and fat metabolism. Diabetes mellitus can be of two types, type 1 and type 2...
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Research Article10.9734/jpri/2021/v33i60A34459
The discovery of insulin was 100 years old till 2021. Insulin, the first diabetic medication, is now the safest and most effective glucose-lowering medication available. Despite its efficacy, the most significant challenge with insulin has been the prevalence of hypoglycemia, whi...
Open access
Research Article10.9734/jpri/2021/v33i57B34067
Obesity has been an emerging health problem worldwide which has a major impact on public health. It is associated with medical, psychosocial and economic implications with increasing prevalence among both adult and paediatric population. Obesity led to an increased risk of medica...
Open access
Research Article10.9734/jpri/2021/v33i55A33817
Introduction: Stroke is the one of the common health problems world-wide causing significant morbidity and mortality. Various scales are framed and validated for use in stroke trials and clinical use. Most widely used scale for stroke assessment is NIHSS scale but this scale is i...
Open access
Research Article10.9734/jpri/2021/v33i39A32157
Background: Preeclampsia & its related problems have potential contribution to maternal mortality & morbidity. Early diagnosis & appropriate management of preeclampsia can prevent antenatal, intranatal & postnatal complications associated with preeclampsia. The ne...
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Research Article10.9734/jpri/2021/v33i62A35142
Vitamin D deficiency affects about 50% of entire people. Vitamin D deficiency affects an estimated 100 million individuals worldwide, spanning all cultures and age groups. This catastrophic situation of vitamin D deficiency can mainly be attributed to lifestyle and the average im...
Open access
Research Article10.9734/jpri/2021/v33i60B34634
Ruptures of the eye normally occur at the point of impact, called a direct rupture, with a strongly focused blow. Because the force is dispersed according to hydraulic law, if the force is more diffuse, the rupture will be indirect and occur in the tunic of sclera of weak locati...
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Research Article10.9734/jpri/2021/v33i60B34681
Background: Anaphylaxis is a medical emergency and requires immediate medical attention. Kounis syndrome is myocardial infarction or injury occurring in the setting of anaphylaxis and can also be due to the effects of epinephrine. Adrenaline is a common drug in the management of...
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Research Article10.9734/jpri/2021/v33i59B34349
Ferritin overload is a frequent problem encountered in patients with beta thalassemia amounting to various complications. One of rare but important complication of ferritin overload is ferritin overload induced toxic encephalopathy. Serum ferritin has been recognised as a importa...
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Research Article10.9734/jpri/2021/v33i57B34052
ECAST Or exercise collapse associated with sickle cell trait is a rare phenomenon associated with sickle cell trait and is an important presentation of sickle cell disease in sports medicine. Collapse is seen following vigorous physical activity, which is due to excessive heat, d...
Open access
Research Article10.9734/jpri/2021/v33i56A33887
With the rapid spread of severe acute respiratory syndrome SARS-CoV2, the incidence of the disease is increasing each day with a higher infectivity rate and unpredictable morbidity and mortality. The second wave in India has higher morbidity and mortality compared to the previous...
Open access
Research Article10.9734/jpri/2021/v33i46B32926
Background: Obesity is a compounded, multifactorial, and largely curable disease, affecting over a third of the public community today. The World Health Organization (WHO) has declared obesity as a global epidemic, also stressing that in many cases it remains an under-recognized...
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Research Article10.9734/jpri/2021/v33i43B32527
Apoplexy of the Pituitary gland is rarely seen critical disorder marked by acute throbbing of head / altered mental status / visual disturbances /decreased consciousness, due to sudden haemorrhagic changes of the pituitary or infarction of the same. There are numerous factors whi...
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Research Article10.9734/jpri/2021/v33i37A31973
Background: Ageing is a global fact affecting both developed and developing countries.It brings out various catabolic changes in body resulting in frailty(i.e. the person is not able to with stand minor stresses of the environment, due to reduced reserves in psychologicalreserve...
Open access
Research Article10.9734/jpri/2021/v33i32B31763
Background: Cirrhosis of the liver is final stage of chronic liver disease [1], which can lead to complications associated with portal hypertension and liver failure. In a much remunerated state, the cirrhotic patient maintains close association to traditional solution and acid–b...
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Research Article10.9734/jpri/2021/v33i64A35314
Non - alcoholic fatty liver disease (NAFLD) is instantaneously progressing to the commonest and dangerous liver disease, with a diverse variety of fat-liver diseases that can progress to extreme hepatic disorders and cirrhosis. Inflammatory processes influence aetiologia of non-a...
Open access
Research Article10.9734/jpri/2021/v33i63A35903
Obesity is defined as a condition in which the amount of adipose tissue in the body is excessive and there has been many researches proving a strong correlation between cardiovascular diseases in obese individuals. The elevated incidence of many identified risk factors including...
Open access
Research Article10.9734/jpri/2021/v33i60B34813
The Severe Acute Respiratory Syndrome (SARS) coronavirus 2 (SARS-CoV2) has spread worldwide at a rapidly alarming pace and has resulted in the coronavirus disease 2019 (COVID-19) pandemic. The virus has more intensive and prolonged standing effects in the host body post-infection...
Open access
Research Article10.9734/jpri/2021/v33i60A34523
We present a case of term pregnancy which presented with chief complaint of Breathlessness, chest pain as well as a one day history of vomiting. She tested positive for COVID19 through reverse transcriptase polymerase chain reaction of nasopharyngeal swab and the symptoms were at...
Open access
Research Article10.9734/jpri/2021/v33i45A32750
Intrinsic endophthalmitis is indeed behavior that causes eye disease that spreads into the bloodstream from a distant primary site. The intraocular disease caused by hematogenous microbial proliferation is known as indigenous endophthalmitis. Extrinsic and intrinsic endophthalmit...
Open access
Research Article10.9734/jpri/2021/v33i60B34585