Objective: The present study aimed to comparatively evaluate floating and non-floating controlled-release formulations of Metformin HCl to understand the influence of formulation composition and processing variables on gastroretentive behavior, drug release characteristics, and p...
Open access
Research Article10.9734/ajrimps/2026/v15i2377
Background & Scope: Ocular drug delivery is inherently limited by anatomical and physiological barriers such as rapid tear turnover, blinking, nasolacrimal drainage, and restricted corneal permeability. These protective mechanisms substantially reduce drug residence time and...
Open access
Research Article10.9734/or/2026/v21i2506
Background & Scope: Pharmaceutical-grade cellulose ethers, such as hydroxypropyl methylcellulose (HPMC) and hydroxypropyl cellulose (HPC), are widely used as excipients due to their effects on viscosity, mechanical strength, hydration behavior, and drug release performance. I...
Open access
Research Article10.9734/jpri/2026/v38i27813
Scope and objective: Objective of this study is to investigate how the combined effects of binder properties and granulation parameters shape the development and performance of controlled-release floating Metformin HCl tablets. It focuses on evaluating the suitability of various...
Open access
Research Article10.9734/jpri/2025/v37i127795
Scope and Objective: Metered-dose inhalers (MDIs) remain the cornerstone of inhalation therapy for asthma and chronic obstructive pulmonary disease (COPD), offering a portable, efficient, and cost-effective means of delivering drugs directly to the lungs. The global MDI market is...
Open access
Research Article10.9734/jpri/2025/v37i127778