Suyash Sawale

In silico Identification of BACE-1 Inhibitory Potential of Indicol from Mangifera indica for Targeting Alzheimer’s Disease

Suyash Sawale, Robin Mathew, Merwyn D’Costa, Nikhil Gadewal, Arvind Singh & Shashibhal Pandey · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2026

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the accumulation of amyloid-beta (Aβ) plaques, primarily formed through the enzymatic action of beta-site amyloid precursor protein cleaving enzyme 1 (BACE-1). There are many synthetic compounds demonstrati...

Open access Research Article 10.9734/ajbgmb/2026/v18i3528

Ferulic Acid as a Potential Drug for Neurological Disorder: An In silico Approach

Suyash Sawale, Robin Mathew, Merwyn D’Costa, Nikhil Gadewal, Arvind Singh & Shashibhal Pandey · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Glycogen synthase kinase-3 (GSK-3) has been known to regulate various cellular and metabolic processes, including neuronal plasticity. Dysregulation of the GSK-3β isoform leads to the development of various neurological disorders such as Alzheimer’s, Parkinson’s, and Huntington’s...

Open access Research Article 10.9734/ajbgmb/2025/v17i3450