V. Senthil Kumar

In silico Molecular Docking Analysis of Imatinib to Target the Marker Proteins of Breast Cancer

V. Senthil Kumar, T. V. Ajay Kumar & V. Parthasarathy · Current Journal of Applied Science and Technology · 2021

Cancer is an uncontrolled over growth of abnormal cells elsewhere in the body. It is the second leading cause of death globally due to non communicable disease. Among the various types of cancers, the incidence of breast cancer is next to lung cancer. The most commonly used drugs...

Open access Research Article 10.9734/cjast/2021/v40i3631579

Assessing the Molecular Interaction between Poly Lactic-co-glycolic Acid (PLGA) 50:50 and Poly Ethylene Glycol in Presence of Diethyl Phthalate Using in silico Study - A Novel Approach of Pre-Formulation Study

V. Senthil Kumar, Navabshan Irfan, T. V. Ajay Kumar & V. Parthasarathy · Journal of Pharmaceutical Research International · 2021

The efficacy of a drug relies on drug formulation and targeting. Imatinib is an anti-cancer drug identified to be effective in the treatment of cancers like myeloid leukemia and lymphoblastic leukemia, and gastrointestinal tumors. The prediction of mixing energy and identificatio...

Open access Research Article 10.9734/jpri/2021/v33i52B33610

Assessing the Specificity of Paclitaxel towards the Marker Proteins of Breast Cancer Using In silico Molecular Docking Study

V. Senthil Kumar, T. V. Ajay Kumar & V. Parthasarathy · Journal of Pharmaceutical Research International · 2020

Breast cancer is highly prevalent next to lung cancer. Breast cancer occurs as a result of mutation in the genes like proto-oncogenes as well as tumor suppressor genes in a single clone of cells in the ductal and glandular regions of the breast. The drugs used to prevent breast c...

Open access Research Article 10.9734/jpri/2020/v32i2430811