Protective Effects of Ascorbic Acid on Gentamicin-induced Nephrotoxicity and Associated Cardiovascular Dysfunctions in Type 1 Diabetic Rats
Temitayo Olabisi Ajibade, Anuoluwapo Bolaji-olutunji, Oluwatofunmi Endurance Onipede, Olaoluwa Isaac Bello, Adewumi Victoria Adeogun, Zaccheaus Akinkunmi Olayiwola, Taiwo Olaide Oyagbemi, Temidayo Olutayo Omobowale, Oluwafemi Omoniyi Oguntibeju, Momoh Audu Yakubu & Ademola Adetokunbo Oyagbemi · International Journal of Biochemistry Research & Review · 2026
Diabetes mellitus is a major risk factor for chronic kidney disease, and the clinical use of effective antibiotics like gentamicin is often limited by its severe nephrotoxicity. This study evaluated the protective effects of ascorbic acid against gentamicin-induced nephrotoxicity...