Zhaohui Ma

The Low Molecular Weight Hyaluronan Fragment HA35 Serves as a Dual Antagonist of Pain-Related Calcium Channels TRPV1 and TRPA1

Xinyue Ma, Joshua Shofaro, Xiaoxiao Jia, Zhaohui Ma & Mizhou Hui · Journal of Pharmaceutical Research International · 2025

Background: Pain, especially chronic pain, remains a major health challenge worldwide. Transient receptor potential (TRP) channels, particularly TRPV1 and TRPA1, play crucial roles in pain perception. Hyaluronic acid (HA), whose bioactivity varies by molecular weight, has shown p...

Open access Research Article 10.9734/jpri/2025/v37i67702

Effectiveness and Safety of 35 kDa Hyaluronan for Symptom Relief in Advanced Lung Cancer: A Pilot Study Focusing on Pain and Cough

B. Sunjidmaa, Dylan Treger, Xiaoxiao Jia, Jessica Hui, Taivanbat Ganbaatar, Bat-erdene Ganbaatar, Zhaohui Ma & Mizhou Hui · Asian Oncology Research Journal · 2025

Background: Advanced lung cancer and its associated pain symptoms place a significant burden on patients. A 35 kDa hyaluronan fragment (HA35) has been confirmed to effectively alleviate inflammatory and neuropathic pain in palliative care settings. This single-arm, prospective pi...

Open access Research Article 10.9734/aorj/2025/v8i1101