Staphylococcus aureus (S. aureus) is one of the most common human pathogens causing various infectious diseases. Further, its ability to form biofilm and the emergence of antibiotic resistance strains has made it difficult to treat the infection. A nanoparticle-based therapeutic...
Open access
Research Article10.9734/jpri/2022/v34i27B36008
Misbahuddin M. Rafeeq, Ziaullah M. Sain, Khwaja Mohd Amir, Najat Binothman, Majidah Aljadani, Ahmad Alzamami, Norah A. Alturki, Abdulrahman Almutairi, Rashed Ahmed Alniwaider, Ahmed Hamdan Aloufi & Alaa Hamed Habib·Journal of Pharmaceutical Research International·2022
The negative effects of leishmanicidal medications are numerous, and drug resistance to all of them has been observed. As a result, new medication development and the identification of novel therapeutic targets are critical. Leishmania major trypanothione reductase (Lm-TR), a NAD...
Open access
Research Article10.9734/jpri/2022/v34i16B35736
Misbahuddin M. Rafeeq, Ziaullah M. Sain, Norah A. Alturki, Ahmad Alzamami, Saeed A. Asiri, Mutaib M. Mashraqi, Amany I. Alqosaibi, Mashael M. Alnamshan, Abdulrahman Almutairi, Abdulkhaliq Munawir Alanazi & Qamre Alam·Journal of Pharmaceutical Research International·2021
Aromatase plays a significant role in the progression of estrogen receptor-positive (ER-positive) breast cancer. The adverse side effects of currently used aromatase inhibitors (AIs) necessitate the development of new AIs that are more active, selective, and less toxic. This stud...
Open access
Research Article10.9734/jpri/2021/v33i32A31717