Introduction: Sickle cell disease (SCD) is characterised by chronic hemolysis, frequent infections, and recurrent occlusions of microcirculation, which cause a painful vaso-occlusive crisis and result in chronic organ damage and failure. Occlusions of the microcirculation and inf...
Aim: This study evaluated reversal effects of single/combined doses of tramadol/sildenafil drugs on haematological and anti-inflamatory cytokines in male albino rats. Study Design: Case control study. Methodology: Forty (40) male albino rats (180-220 g body weight) were grouped i...
Jacques Ossinga Bassandja, François Lusamaki Mukunda, Gaspard Mande Bukaka, Joris Losimba Likwela, Camille-Remy Atoba Bokele, Charles Kayembe Tshilumba & Salomon Batina Agasa·Asian Hematology Research Journal·2018
Objective: To determine the seroprevalence of carriage of Hepatitis B surface antigen among blood donors in Isangi, a rural health area in northeastern DR Congo. Methods: This was a retrospective study conducted in the Isangi Rural Health Zone from January 1, 2010 to December 31,...
Jacques Ossinga Bassandja, François Lusamaki Mukunda, Gaspard Mande Bukaka, Serge Tonen Wolyec, Camille-Remy Atoba Bokele, Charles Kayembe Tshilumba & Joris Losimba Likwela·Asian Hematology Research Journal·2018
Introduction: Blood safety is a serious public health concern for health authorities in sub-Saharan African countries. Blood transfusion is a major mode of transmission of viral hepatitis B. The objective of this study is to determine the prevalence of carriage of HBs antigen amo...
Joseph Aondowase Orkuma, Julie Ochaka Egesie, Simji Samuel Gomerep & Ejele Osaikhuemen Adebayo·Asian Hematology Research Journal·2018
Background: Global targets of providing safe blood available universally by 2020 as well as that seeking to eliminate HIV transmission by 2030 has compelled many hospital-based blood banks to employ relevant strategies in their transfusion practice towards realizing these targets...
Introduction: von Willebrand Factor (VWF) plays a vital role in platelet aggregation. The unusually large VWF multimers mediate the adhesion of sickle red blood cell (RBC) to endothelial cells and contribute to vaso-occlusive episodes. Objective: The aim of this study was to dete...
The aim of this investigation is to determine tHcy levels in SCD Omani Arabs in (i) the steady state (ii) crisis (iii) relative to non-SCD subjects as such values might help clarify the role of tHcy in SCD. Serum tHcy concentrations and other laboratory analyses including serum...
Background: The degree of platelet activation may be assessed by platelet indices such as platelet count (PC), mean platelet volume (MPV) and platelet distribution width (PDW). Platelet indices are potentially predictive, diagnostic and prognostic useful markers for platelet-rela...
B. Chetcha Chemegni, A. V. Kouam Kaping, I. Ngosso Tetanyé, A. Bodieu Kenmegne, L. Kouemeni, G. Ngouefo, E. K. Ola Bamzok, Tetanye Ekoe & L. Kaptué Noche·Asian Hematology Research Journal·2018
Sickle cell disease is the most frequent genetic disease worldwide with high mortality and morbidity rates. Several therapeutic medications have been put in place amongst which hydroxurea, an antineoplastic for which the clinical-biologic benefits for the patients have been estab...
Though concerns over the safety of medicinal drugs are following rife consumption of some herbal preparations, the underlying pathogenesis remains however cryptic. Awareness of the far-reaching effects of herbal preparations is germane to their continued use in traditional medici...