Justicia insularis (Acanthaceae) T. Anderson, a vegetable also used in treating a number of diseases locally was tested for effect on doxorubicin (Dox)-induced liver damage. The plant's leaf extract (100 - 400 mg/kg) and fractions (dichloromethane (DCM) and aqueous) (200 mg/kg) w...
Open access
Research Article10.9734/ajbgmb/2026/v18i9565
Methamphetamine (METH) can induce oxidative stress and structural injury in the cerebral cortex, whereas vitamin A participates in antioxidant defence and neural maintenance. This study evaluated the effect of low-dose vitamin A on methamphetamine-induced cortical changes in adul...
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Research Article10.9734/ajbgmb/2026/v18i9564
Background: This study investigated the anti-inflammatory and antioxidant activities of leaf fractions and their effects on selected biochemical indices. Methods: A crude ethanolic leaf extract was partitioned using n-hexane, ethyl acetate, and ethanol. Phytochemical constituents...
Open access
Research Article10.9734/ajbgmb/2026/v18i9563
Phytochelatins are glutathione-derived peptides involved in heavy-metal chelation and sequestration in plants. This study aimed to molecularly identify the phytochelatin synthase 1 (PCS1) gene in Eichhornia crassipes collected from the heavy-metal-contaminated Panteka stream in K...
Open access
Research Article10.9734/ajbgmb/2026/v18i8562
Onyema Kelechi Roselyn, Faith Tobore Edafetanure-Ibeh, Taiye Babalola Joy, Ifeanyi Raphael Ugwuanyi, Oyeocha Chinenye Vivian, Chiemeka Elochi Emeribe & Possible Okikiola Popoola·Asian Journal of Biochemistry, Genetics and Molecular Biology·2026
The reproductive organs are conventionally treated as the effectors of a hierarchical endocrine axis, yet the evidence accumulated over the past three decades indicates that their structure and functional capacity are substantially specified by events occurring in the developing...
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Research Article10.9734/ajbgmb/2026/v18i8561
This study investigated the effects of consuming three species of stockfish (Haddock, Apama, and Cod) sold in Port Harcourt on liver and kidney biomarkers in Wistar rats. Forty Wistar rats were divided into eight groups of five rats each. The first group served as the control, wh...
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Research Article10.9734/ajbgmb/2026/v18i8560
Background: Pentachlaena latifolia (Sarcolaenaceae) is an endemic Malagasy species whose phytochemical composition and antioxidant potential remain insufficiently documented. This study characterised the phytochemical profile and evaluated the antioxidant activity of its leaf ext...
Open access
Research Article10.9734/ajbgmb/2026/v18i8559
Hypertension is a major risk factor for renal and cardiovascular diseases, and angiotensin-converting enzyme (ACE) inhibitors are among the principal therapeutic agents used in its management. This study aimed to predict the ACE-inhibitory activity of unripe C. papaya fruit extra...
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Research Article10.9734/ajbgmb/2026/v18i8558
Medicinal plants remain important sources of bioactive compounds with potential therapeutic value, including agents that may support cancer drug discovery. This study evaluated the selective anticancer effect of Diospyros mespiliformis aqueous leaf extract against MCF-7 breast ca...
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Research Article10.9734/ajbgmb/2026/v18i8557
Background: Diabetes mellitus is a lingering and persistent metabolic disease categorized by an inadequate insulin secretion or action. The rise in type 2 diabetes mellitus (T2DM) globally has increased the quest for an alternative therapeutic candidate. Drosophila melanogaster (...
Open access
Research Article10.9734/ajbgmb/2026/v18i7555