A rugged robust RP-HPLC method has been developed and validated for the simultaneous quantification of Aspirin (ASP), Atorvastatin calcium (ATO) and Clopidogrel bisulphate (CLO) in a combined dosage form. Optimized mobile phase composition of 25 mM KH2PO4: Methanol (20:80% v/v) p...
Open access
Research Article10.9734/ajocs/2019/v6i419003
A series of Chloro-arsenic(III) complexes with N, O donor β-ketiminate ligand (L1) and S, S donor piperidine dithiocarbamate ligand (L2) have been synthesized by the reactions of AsCl3 with both ligands in equimolar ratio by stirring at room temperature in benzene solution. All...
Open access
Research Article10.9734/ajocs/2019/v6i419002
Salicylaldehyde semicarbazone ligand and its Cu (II) complex have been synthesized and characterized by a range of physicochemical methods. Experimental data shows the complex is monomeric and the copper atom is four coordinated in a square planar geometry. The ligand chelates th...
Open access
Research Article10.9734/ajocs/2019/v6i419001
Drug molecule contains various reactive functional groups which are susceptible to react with another reactive functional groups which might be excipients, excipient or drugs impurities formed during manufacturing or storage. The objective of the current review article is to prov...
Open access
Research Article10.9734/ajocs/2019/v6i319000
Hydrogel which can swell rapidly and retain large volumes of water in their swollen structure have shown a significant contribution for wound healing. More recently, hydrogel synthesized by radiation polymerization and grafting have been reported which did not require any crossli...
Open access
Research Article10.9734/ajocs/2019/v6i318999
This research is aimed at the proximate chemical analysis of Momordica balsamina seeds with some properties of the oil. The results of the study showed that the seeds has high percentage of crude lipids, (38.77±0.15%) crude carbohydrates, (31.46±0.14%), crude proteins, (20.25±0.1...
Open access
Research Article10.9734/ajocs/2019/v6i318998
Background: Bacterial infections are at the origin of a number of serious pathologies, including meningitis, bronchopneumopathies, typhoid fever and especially diarrhea, which are still a real public health problem for the child population in developing countries. In most of thes...
Open access
Research Article10.9734/ajocs/2019/v6i318997
Chalcones are useful intermediates in the synthesis of heterocyclic compound and the unique reagents in organic synthesis. The usual approach to obtain chalcones is through Claisen-Schmidt condensation. Several novel heterocyclic chalcone analogs have emerged. Chalcones are multi...
Open access
Research Article10.9734/ajocs/2019/v6i318996
Determination of heavy metal contents in edible clay (kaolin) from Enyigba in Abakaliki, Ebonyi State of Nigeria was carried out using Atomic absorption Spectrophotometer (AAS). The quantitative analysis of heavy metal analyzed in the edible clay sample were 0.012 mg/kg for Co, 0...
Open access
Research Article10.9734/ajocs/2019/v6i218995
Aim: To screen the Kenyan Ganoderma lucidum for phytochemicals and to investigate it's potential in the management of some disease-causing microbes. Study Design: Hexane, ethyl acetate and methanol extraction; phytochemical study and anti-microbial activities were analysed on Ken...
Open access
Research Article10.9734/ajocs/2019/v6i218994