Background: In early childhood, type 1 diabetes mellitus (T1DM) is an autoimmune illness marked by the death of pancreatic β-cells by the immune system. Autoantibodies that are important indicators of illness etiology and diagnosis include insulin autoantibodies (IAA), glutamic a...
Open access
Research Article10.9734/aji/2026/v9i1182
Background: Rotavirus is a leading cause of severe diarrhea among children under five years of age globally, with Nigeria bearing a significant burden. Despite the introduction of the rotavirus vaccine into Nigeria’s national immunisation schedule, uptake remains suboptimal in ma...
Open access
Research Article10.9734/aji/2026/v9i1181
Routine childhood immunization remains one of the most cost-effective public health interventions, yet Nigeria continues to experience substantial gaps in coverage, timeliness, and completion of recommended vaccine series. These gaps are not uniform: they cluster by geography, so...
Open access
Research Article10.9734/aji/2026/v9i1180
Background: Edible chalk (Nzu), a geophagic kaolin widely consumed in several African communities, particularly among women, has been associated with both perceived health benefits and potential toxicological risks. This study investigated the immunomodulatory effects of edible c...
Open access
Research Article10.9734/aji/2026/v9i1179
Tuberculosis (TB) is the second most deadly airborne infectious disease caused by Mycobacterium tuberculosis, posing a major global health risk dw. Nearly one-third of the world’s population is infected, with low-income countries most affected due to limited access to diagn...
Open access
Research Article10.9734/aji/2025/v8i1178
Islam Ariremako Jimoh, TOBECHI BRENDAN NNANNA, TAIWO MICHEAL OLUMUJI, Paul Onyekachi Ukegbu, Michael Sewanu Hungbo & Kanime Hussaini·Asian Journal of Immunology·2025
Background: Immune checkpoint blockade (ICB) has transformed oncology, but its efficacy is limited by primary and acquired resistance. The gut microbiome is a established determinant of ICB response, while neutrophil extracellular traps (NETs) have recently emerged as key mediato...
Open access
Research Article10.9734/aji/2025/v8i1177
Background: Tumour necrosis factor alpha (TNF-α) and Adiponectin are both Pro and anti-inflammatory cytokines that play major roles in the pathogenesis and therapeutic management of many metabolic diseases. Aim: This study aimed at evaluating the role of TNF-α and Adiponectin amo...
Open access
Research Article10.9734/aji/2025/v8i1176
Hayder Abdul Hussein Abass, Zainab Abdul Kareem Ataia, Ihsan K. A. Alkardhi & Hayder Ali Muhammed·Asian Journal of Immunology·2025
Oral candidiasis, caused predominantly by Candida albicans, represents one of the most common opportunistic fungal infections in pediatric populations. This study investigates the immunological responses and molecular characterisation of Candida colonisation in the oral cavities...
Open access
Research Article10.9734/aji/2025/v8i1175
Immune-mediated diseases, including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), multiple sclerosis (MS) and Inflammatory Bowel Disease (IBD: Crohn's Disease & Ulcerative Colitis) represent a significant global health burden characterized by a loss of immune...
Open access
Research Article10.9734/aji/2025/v8i1174
Hacene Meriche, Sara Zaghez, Feriel Sandra Bouafia, Boutheina Abdaoui, Nacima Sabiha Gadiri & Hichem Frigaa·Asian Journal of Immunology·2025
Multiple myeloma (MM) in pregnant women is a rare disease characterized by clonal proliferation of plasma cells producing monoclonal immunoglobulin, which suppresses the normal production of other antibodies and weakens the maternal immune response. Plasma cells release inflammat...
Open access
Research Article10.9734/aji/2025/v8i1173