Gestational diabetes mellitus (GDM) is a common metabolic abnormality which affects approximately 2-5% of pregnancies. Risk factors such as previous infants with macrosomia, strong family history of type 2 diabetes or GDM, poor glycaemic control and high pre-pregnancy body mass i...
Open access
Research Article10.9734/ajrimps/2019/v6i230097
Background: Inflammation is said to be associated with hyperglycaemia and is implicated in the complications of diabetes. Aim: This study was designed to investigate the level of some inflammatory markers in blood of diabetic rats administered with aqueous leaf extract of Termina...
Open access
Research Article10.9734/ajrimps/2019/v6i230098
Background: The endocrinal abnormalities in diabetes mellitus as one of the numerous metabolic disorders is associated with derangement in exocrine functions of the pancreas and ultimately influences blood glucose regulation. Aim: The study was aimed at assessing the role of alph...
Open access
Research Article10.9734/ajrimps/2019/v6i230096
Thaumatococcus danielli (Benn.) Benth, a member of the Maranthaceae family has continued to be of immense benefit to the people in the tropics especially in Nigeria. The leaf is widely used among the “Yoruba’s” as a wrapping leaf and for the management of diabetes mellitus. Aim:...
Open access
Research Article10.9734/ajrimps/2019/v6i230095
Stability testing confirms the safety and quality of an active pharmaceutical ingredient or product. The shelf life of Picralima nitida (herbal drug) and glibenclamide were evaluated using the bio-based dose-response relationship method by the use of animal model based on their p...
Open access
Research Article10.9734/ajrimps/2019/v6i130094
Aim: To investigate the laxative potentials of aqueous leaf extract of Sida acuta in loperamide-induced constipation in Wistar rats. Methods: Constipation was induced by oral administration of loperamide (3 mg/kg b.wt.). The constipated rats were orally treated daily either with...
Open access
Research Article10.9734/ajrimps/2019/v6i130093
Aim: The aim of the study was to correlate anthropometric data with atherogenic indices of students in Rivers State University, Port Harcourt as a means of assessing their cardiovascular health. Study Design: A pilot study was carried out in Rivers State University, Port Harcourt...
Open access
Research Article10.9734/ajrimps/2019/v6i130092
Aim: The shelf-life of Picralima nitida (herbal drug) and two orthodox drugs (ciprofloxacin, and pefloxacin) has been examined. Methodology: The stability studies were carried out using the bio-based concentration-activity relationship technique. Accelerated stability studies wer...
Open access
Research Article10.9734/AJRIMPS/2019/46309
Following long-term consumption of kola nut (Cola nitida) diet, anxiety related behaviour were studied in 16 Swiss white mice (18-28g body weight). The open field (OF) test, elevated plus maze EPM) and the light/light transition box (LD) tests were used. Swiss white mice were fed...
Open access
Research Article10.9734/AJRIMPS/2019/45797
Aim: To investigate the histological effect of ethanolic extract of Tridax procumbens leaf commonly used as medicinal plant, on potassium bromate induced nephrotoxicity in adult Wistar rats. Place and Duration of Study: Department of Anatomy, Faculty of Basic Medical Sciences, Ab...
Open access
Research Article10.9734/AJRIMPS/2018/46121