Inflammation is inseparable from blood-cell biology: circulating cells detect inflammatory cues, bone-marrow progenitors alter lineage output, erythroid iron supply is actively restricted, and haemostatic pathways can be recruited as components of host defence. Yet the expression...
Open access
Research Article10.9734/ibrr/2026/v17i4396
Background: Routine haematological and biochemical indices support monitoring of adults with HIV, but geographical variation in Rivers State is insufficiently described. Aims: To compare blood count indices, inflammatory cell ratios, biochemical parameters and physical indicators...
Open access
Research Article10.9734/ibrr/2026/v17i4395
Background: Nigeria is home to more than two million people living with HIV, yet it remains underrepresented in HIV vaccine trials. Peripheral blood mononuclear cells (PBMCs) are vital for assessing vaccine-induced immunity; however, biobanking in resource-limited settings presen...
Open access
Research Article10.9734/ibrr/2026/v17i4394
Background: Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder characterised by persistent synovial inflammation and progressive joint damage. Aim: This study assessed selected autoimmune and inflammatory biomarkers among individuals with RA in Port Harcourt,...
Open access
Research Article10.9734/ibrr/2026/v17i4393
Background: Male reproductive dysfunction is increasingly relevant in chronic anaemias as survival into adulthood has improved in β-thalassaemia and sickle cell disease, while iron-deficiency anaemia remains globally common. Impaired fertility arises through hypoxia, oxidative st...
Open access
Research Article10.9734/ibrr/2026/v17i4392
Blood group typing has changed more in the past three decades than in the preceding hundred years. What began as an exercise in observing agglutination reactions has become, increasingly, an exercise in reading DNA: a shift from describing antigens as they appear on the red cell...
Open access
Research Article10.9734/ibrr/2026/v17i4391
Kouamé Norman Isaac Klébair, Kamara Ismael, Assohou Hiabba Emmanuela, Atseye Chiadon Carele Charlene, Kouadio Emmanuel, Boidy Kouakou & Gustave Kouassi Koffi·International Blood Research & Reviews·2026
Spontaneous non-traumatic epidural haematoma is an uncommon but potentially fatal neurological complication of sickle cell disease. This case report describes a 13-year-old girl with homozygous sickle cell disease who was admitted with a non-febrile vaso-occlusive crisis after in...
Open access
Research Article10.9734/ibrr/2026/v17i4390
Chiemelie Raluchukwu Onwasigwe, Michael Chidiebele Egolum, Angela Ogechukwu Ugwu & Hector Okechukwu Obianyido·International Blood Research & Reviews·2026
Background: Non-Hodgkin lymphoma is a heterogeneous group of lymphoid malignancies with variable clinical behaviour and treatment outcomes. In resource-constrained settings, limited access to advanced prognostic investigations increases the need for simple biomarkers. This study...
Open access
Research Article10.9734/ibrr/2026/v17i3389
Adenuga Jacob Olaitan, Olusegun Taiwo Oke, Muhibi Musa Abidemi, Adesina Beatrice Ebun, Olatunji Oluwatobi, Ajao Oluwadare Amos & M. B. Ajayi·International Blood Research & Reviews·2026
Hemoglobinopathies (e.g., HbS, HbC, HbF) are the most common single-gene disorders worldwide, especially in sub-Saharan Africa. Beyond affecting red blood cells and oxygen transport, they significantly disrupt blood clotting (hemostasis) and blood flow properties (haemorheology)....
Open access
Research Article10.9734/ibrr/2026/v17i3388
Ndudi Dibigbo–Ibeaji, Sylvia Ifeoma Obu, Gabriel Obisike Obu, Samuel Okwuchukwu Ilikannu, Akinkunmi Ibukun Jacob & Ezunu Ngozi Esther·International Blood Research & Reviews·2026
Background: Pancytopenia reflects a failure of normal hematopoiesis or excessive destruction or sequestration of blood cells and is frequently associated with significant morbidity and mortality if not promptly identified and managed. Despite growing global recognition of the sys...
Open access
Research Article10.9734/ibrr/2026/v17i3385