Aim: To analyze different HNH endonucleases from various sources including the HNH endonuclease regions of CRISPR-Cas9 proteins for their conserved motifs, metal-binding sites and catalytic amino acids and propose a plausible mechanism of action for HNH endonucleases, using CRISP...
Open access
Research Article10.9734/ijbcrr/2020/v29i630192
Aims: This study was designed to assess antiplasmodial and antioxidant activities in relation to phytochemical contents and toxicological profile of crude extracts of Cola millenii leaves. Place and Duration of Study: The study was carried out from April 2015 to November 2018 at...
Open access
Research Article10.9734/ijbcrr/2020/v29i530191
Background: Diabetes mellitus is a metabolic disease characterized by hyperglycaemia over a prolonged period. In Uganda, unripe Musa paradisiaca (banana) is a staple food which is deskinned before cooking. In West Africa, however, the unpeeled banana is cooked for diabetics. Aim:...
Open access
Research Article10.9734/ijbcrr/2020/v29i530190
Background: Antibiotic resistance among pathogenic bacteria is increasing at an alarming rate leading to the need for traditional medicine as an alternative. Aim of the Study: The study aimed to evaluate the antimicrobial activity of methanolic and, aqueous extracts of partial pu...
Open access
Research Article10.9734/ijbcrr/2020/v29i530189
Aim: To evaluate the anti-oxidant enzymes, lipid peroxidation, lipid profile and liver function in albino rats orally administered tartrazine. Study Design: A total number of 63 female albino rats weighing approximately 0.2 kg were used for this study. The study was divided into...
Open access
Research Article10.9734/ijbcrr/2020/v29i530188
The determination of the effect of processing on nutritional composition and level of undigested oligosaccharide in Cucumeropsis mannii seeds was carried out. The dried melon seeds were sorted, cleaned, soaked in 60mL water for 15 min for easy removal and de-hulled to get the cot...
Open access
Research Article10.9734/ijbcrr/2020/v29i530187
This study investigated the in-vitro antioxidant activity of ethanol leaf extract of Justicia carnea and its effect on antioxidant status of alloxan-induced diabetic albino rats. The in-vitro antioxidant activity was assayed by determining the total phenol, flavonoids, ascorbic a...
Open access
Research Article10.9734/ijbcrr/2020/v29i430185
Coronavirus (CoVs) is a large family of enveloped, single-stranded, positive-sense RNA viruses that infect a wide range of vertebrates. They are extensively found in bats and also in many other birds and mammals including humans. SARS-CoV-2 is a global pandemic and originated fro...
Open access
Research Article10.9734/ijbcrr/2020/v29i530186
This study was undertaken to evaluate the effect of different processing methods on extraction of millet milk viz., germinated millet milk extraction, germinated and roasted millet milk extraction; enzyme assisted millet milk extraction and ultrasonicated millet milk extraction....
Open access
Research Article10.9734/ijbcrr/2020/v29i430184
Background: The extract of Hibiscus sabdariffa commonly known as Sobo is widely consumed for its nutritional and health benefits. This study investigated the effect of aqueous leaf extract of H. sabdariffa on anemic condition caused by phenylhydrazine in rats. Materials and Meth...
Open access
Research Article10.9734/ijbcrr/2020/v29i430183