The effect of boiling, steaming and microwaving on proximate and mineral compositions of fluted pumpkin (Telfairia occidentalis) leaves were investigated. Standard methods of analyses were applied for the determinations of selected parameters. Results obtained indicated that at P...
Open access
Research Article10.9734/IJBCRR/2016/21483
Aims: To purify and characterize the smallest lectin from Datura innoxia (DiL9) and to evaluate its antimicrobial application potential. Study Design: Protein purification and characterization using biochemical and biophysical techniques. MALDI-MS/MS for peptide mass finger print...
Open access
Research Article10.9734/IJBCRR/2016/22157
In the present study, Secoisolariciresinol diglucoside (SDG) was synthesized from commercially available 3,4-dimethoxytoluene, butanediol and penta acetyl glucose. This includes bromination, alkylation, glycosylation, deacetylation and demethylation reactions to yield the interes...
Open access
Research Article10.9734/IJBCRR/2016/22277
The present study was carried out to screen phytochemicals like carbohydrates, terpenoids, resins, saponins, tannins and alkaloids in the seed extract of Areca catechu by standard protocols and antibacterial activities of seed extract as well as silver nanoparticles prepared from...
Open access
Research Article10.9734/IJBCRR/2016/21864
Background: Fermented gruel (Ogi) has been reported to have high lactic acid bacteria (LAB) with proven probiotic properties. This fermented food has also has different therapeutic usages. Objective: The activities of fermented sorghum (Ogi) on induced hypercholesterolemia in alb...
Open access
Research Article10.9734/IJBCRR/2016/19659
Adipose tissue is a key player in whole body metabolism and excess adipose tissue poses a major risk factor for the development of metabolic disorders such as type 2 diabetes. In response to nutritional overload, de novo adipocyte differentiation can serve as an adaptive mechanis...
Open access
Research Article10.9734/IJBCRR/2016/18221
Background and Objectives: Polycystic ovarian disease (PCOS) is probably the most prevalent endocrinological disorder affecting females and is the most common cause of menstrual disturbance during the reproductive age. It is characterized by polycystic ovaries on ultrasound and/o...
Open access
Research Article10.9734/IJBCRR/2016/21676
The aim of this study was to determine the median lethal dose (LD50) of the extracts (aqueous and ethanol) of S. hispidus stem bark. A modified Lorke’s (1983) method was used in this study. Varying doses of the extracts were administered orally to male albino rats. Treatment-rela...
Open access
Research Article10.9734/IJBCRR/2016/22036
Endoglucanase (EC3.2.1.4) from sorghum (S. bi-color) and millet (Pennisetum typhoides & Digitaria exilis) malts were purified to homogeneity through the methods of ammonium sulphate precipitation and gel filtration. Molecular mass of 35 KDa and 41 KDa were determined by SDS-P...
Open access
Research Article10.9734/IJBCRR/2015/20593
Aim: We examine in this study the effect of two antitumor drugs metothrexate (MTX) and carboplatin (CPT) on the phospholipid content of plasma membrane of MCF-7 breast cancer cells. MTX is a folate analog that inhibit dihydrofolate reductase. CPT is a platinum-containing antineop...
Open access
Research Article10.9734/IJBCRR/2015/20709