Currently all approved PD-1/PD-L1 inhibitors are monoclonal antibodies. Along with that, compounds from other chemical classes are being investigated as well. Among those are small molecules which demonstrate commensurable therapeutic effect in preclinical and early clinical deve...
Background : Vulva cancer is a rare but important genital tract malignancy. Aims: This pioneer study was to determine the prevalence, sociodemographics, clinical présentation, histological pattern and treatment outcome at the University of Port Harcourt Teaching Hospital (UPTH)....
Introduction: Cervical Cancer is the second most common cancer among women in India. Majority of the patients are diagnosed in an advanced stage. Stage IIIB Cervical cancer include those with pelvic side wall involvement or hydronephrosis. Presence of hydronephrosis negatively af...
Obesity has become an important public health problem all over the world with its increasing rate. Therefore, the frequency of encountering with this patient group in our anesthesia practice is increasing. Our patient was a 60 years-old woman. Her height was 150 cm, her body we...
Introduction: Cirrhosis is defined as the histological development of regenerative nodules surrounded by fibrous bands in response to chronic liver injury that leads to portal hypertension and end stage liver disease. Although the causes are interwoven, some pathological characte...
Aims: Carboxylesterases (CE) convert carboxylic esters to alcohols and carboxylic acids. CE is a protective factor in the brain cells categorized as phase-I drug-metabolizing enzymes. Therefore we aim to find out the difference CE specific activity for Brain tumors as compared to...
Renal carcinoma is a tumor with high metatstatic risk, compromising its prognosis, often fatal. Involvement in the inferior vena cava is present in 15-20% of metastatic locations with the possibility of intracavitary cardiac extension in 5%. The circumstance of discovery of this...
Smoldering multiple myeloma (SMM) is a clonal plasma cell (PC) condition that falls between monoclonal gammopathy of unknown significance (MGUS) and multiple myeloma (MM). Detecting SMM patients allows for early therapy, which slows the disease's course and reduces morbidity. Thi...
Smooth muscle tumors originating from round ligament are rarewith leiomyoma being the most common type among them with unknown exact incidence. Its location at inguinal area/pubic area is confused with the clinical diagnosis of vulvar swelling, inguinal hernia, lymph node, or oth...
A 52-year-old patient from Bangladesh, known for hypertension for the last year, was taking oral antihypertensives. Nonetheless, he still had uncontrolled blood pressure, and no associated symptoms. The patient was referred to Emergency with a presenting complaint of high blood p...