International Research Journal of Pure and Applied Chemistry

Prediction of the Inhibitory Concentration of Hydroxamic Acids by DFT-QSAR Models on Histone Deacetylase 1

Doh Soro, Lynda Ekou, Mamadou Guy-Richard Koné, Tchirioua Ekou, Sopi Thomas Affi, Lamoussa Ouattara & Nahossé Ziao · International Research Journal of Pure and Applied Chemistry · 2018

In order to study the relationship between inhibitory concentration and the molecular structures of hydroxamic acids, a Quantitative Structure Activity Relationship (QSAR) study is applied to a set of 31 histone deacetylase inhibitors (HDACi). This study is performed by using the...

Open access Research Article 10.9734/IRJPAC/2018/40895

Synthesis, Characterization and Antibacterial Studies of Some Metal Complexes of N-DI (Pyridin-2-YL) Thiourea Derivatives

Omotola M. Fayomi, R. Sha’Ato, Raymond A. Wuana, John O. Igoli, Vashen Moodley & Werner E. Van Zyl · International Research Journal of Pure and Applied Chemistry · 2018

N-(di (pyridin-2-yl) carbamothioyl)-3-nitrobenzamide (L1) and N-(di(pyridin-2-yl) carbamothioyl)-4-nitrobenzamide (L2)) and their copper (II), nickel (II), cobalt (II) and zinc (II) complexes have been synthesized, characterized and tested for antibacterial activity. The ligands...

Open access Research Article 10.9734/IRJPAC/2018/40567

Preparation and Characterization of Methacrylic Acid-based Molecularly Imprinted Polymer as a New Adsorbent for Recognition of 1,4-dihydroxybenzene

Kehinde N. Awokoya, Vincent O. Oninla, Iyanuoluwa T. Adeleke & Jonathan O. Babalola · International Research Journal of Pure and Applied Chemistry · 2018

This article presents the first example of sequentially reported template removal procedure in molecularly imprinted polymers (MIPs) using UV-spectrophotometer. Polymerization was achieved in a glass tube containing 1,4-dihydroxybenzene (DHB) template molecule, methacrylic acid (...

Open access Research Article 10.9734/IRJPAC/2018/38586

Phase Diagrams, Molal Volumes and Polarizabilities of (Lysine, Methionine Amino Acids-Alcohol-Water) Tri-Component Systems

Farid I. El-Dossoki · International Research Journal of Pure and Applied Chemistry · 2018

The molal solubility, density and refractive index of DL-Methionine (as a nonpolar neutral amino acid) and L-Lysine (as polar basic amino acid) in water–methanol and water–ethanol mixed solvents with alcohol mole fractions (0.0, 0.10, 0.30, 0.50, 0.70, 0.90, and 1.0, by volume) a...

Open access Research Article 10.9734/IRJPAC/2018/40184

Use of Borosilicate Glass as Fluxing Agent to Enhance the Physio-mechanical Properties of Bricks

Md. Sagirul Islam, Umme Sarmeen Akthar & Khondoker Shahin Ahmed · International Research Journal of Pure and Applied Chemistry · 2018

The aim of this study is to investigate the effect of borosilicate glass as a flux on the Physio-mechanical properties of the brick. To do this job brick sample was prepared by incorporating borosilicate (BS) glass with red clay in different proportions like 20%, 35%, and 50% and...

Open access Research Article 10.9734/IRJPAC/2018/40003

The Effect of Different Acid Chloride on Physical and Chemical Characterizations of Aryledinecycloalkanone Unsaturated Copolyesters

Momen S. A. Abdelaty, Abdel Haliem M. Hussien, Mohamed S. El-gaby, Mohamed Gad-Elkareem, Sayed M. Abas, Yasser. B. Saddeek, Dirk Kuckling & Kamal I. Ali · International Research Journal of Pure and Applied Chemistry · 2018

Unsaturated copolyesters have been prepared and evaluated by chemical and physical instruments. The effect of acid chloride in the general physical characterizations of copolyesters was the aim of study. The solubility of polymers has been tested in different solvents. The viscos...

Open access Research Article 10.9734/IRJPAC/2018/40643

Green and Environmentally Benign Organic Synthesis by Using Fruit Juice as Biocatalyst: A Review

Suman ., Anjani ., Suprita ., Sheetal, Susheel Gulati & Rajvir Singh · International Research Journal of Pure and Applied Chemistry · 2018

Facile and green synthetic approaches are important issues in organic synthesis. Green chemistry has become a motivational and inspirational tool for organic chemists to develop mild and benign pathways for the synthesis of biologically active compounds. The naturally available f...

Open access Research Article 10.9734/IRJPAC/2018/40536

Accelerated Storage Stability of Refined Cotton Oil in Term of Free Fatty Acid and Thiobarbituric Acid

Anjani . & Rajvir Singh · International Research Journal of Pure and Applied Chemistry · 2018

Aims: To study accelerated storage stability of refined cotton oil in term of free fatty acid and thiobarbituric acid. Place and Duration of Study: Department of Chemistry and Biochemistry, CCS Haryana Agricultural University, Hisar-125004, India, between January 2014 to continui...

Open access Research Article 10.9734/IRJPAC/2018/40401

Synthesis and Charaterization of Metal Chelates of (5-(2,3-dimethyl-1-phenyl-3-pyrazolin-5-one-4-ylazo)-1H-pyrimidine-2,4-dione)

V. G. Vidya · International Research Journal of Pure and Applied Chemistry · 2018

An azo dye UAAP and Mn(II), Co(II), Ni(II), Cu(II) and Zn(II)complexes were synthesized and characterized using elemental analysis, mass spectra, UV- Vis, fluorescence spectra, ESR spectrum, IR spectra, NMR spectra, NLO property, molar conductance and magnetic measurements. The s...

Open access Research Article 10.9734/IRJPAC/2018/37899

The Recyclable Bronsted Acidic Liquid Resin Mediated Eco-benign Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones and 3,4-Dihydropyrimidin-2(1H)-thiones via Biginelli Reaction

D. Parthiban, R. Joel Karunakaran & C. J. Magesh · International Research Journal of Pure and Applied Chemistry · 2018

Aim: To synthesis 3,4-Dihydropyrimidin-2(1H)-ones and 3,4-Dihydropyrimidin-2(1H)-thiones using phenol formaldehyde resin as a catalyst. Study Design: Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones and 3,4-Dihydropyrimidin-2(1H)-thiones by cyclocondensation of ethyl or methyl acetoa...

Open access Research Article 10.9734/IRJPAC/2018/40035