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Journal of Advances in Medical and Pharmaceutical Sciences

Published by SCIENCEDOMAIN international · ISSN (electronic) 2394-1111

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889

Articles indexed

63

2026 articles

889

Open access

3,567

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Articles (889)

5HT1a Receptor Binding Affinities of a Series of Serotonin Transporter (SERT) Inhibitors and Related Thermodynamic Insights^

Gisella E. Alfonsino, Andrea Santagati, Livia Basile, Ettore Novellino, Corey Gaul, Carley Squires, Michael Braden, John M. Gerdes, Silvia Pérez Silanes, Salvatore Guccione & Keith K. Parker · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Clinical depression encompasses a complex neurobiology involving multiple interacting systems. This intricate pathophysiology is, in part, correlated with dysfunction in serotonin (5HT) neurochemistry. The 5HT1a receptor (R) and SERT (serotonin transporter) components of this net...

Open access Research Article 10.9734/JAMPS/2015/18917

A Pilot Study on the Association Between Trunk Hair Density and Insulin Resistance in Nonobese Turkish Men

Nilay Duman & Betül Aydın Buyruk · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Aim: The association between insulin resistance and hirsutism in women is well studied.  However there is no previous data about association between insulin resistance and male body hair density. Thus, the aim of the present study is to evaluate association between insulin resist...

Open access Research Article 10.9734/JAMPS/2015/19450

Clinical Use and Complications of Peripheral Venous Cannulae among Adult Patients in a Nigerian Tertiary Hospital, Benin City: A Pilot Study

S. Adewoyin Ademola & O. Ogunnowo Tolulope · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Background: Peripheral venous catheterization is a common medical procedure among hospitalized patients. Its use is fraught with potential complications including thrombophlebitis and blood stream infections. This necessitates provision of appropriate local protocols, meticulous...

Open access Research Article 10.9734/JAMPS/2015/19223

Design of COX-1 Inhibitors Utilizing Class I Isosteres, Class II Isosteres, and Nonclassical Bioisosteres for Substituent Substitution on Proved Parent Structures

Ronald Bartzatt · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Aims: To identify isosteres and bioisosteres suitable for substitution on the molecular scaffold of meclofenamic acid and tolfenamic acid. The compounds will be studied to determine drug-likeness and other properties. Study Design: Isosteres and bioisosteres were selected and emp...

Open access Research Article 10.9734/JAMPS/2015/18954

Eruptive Seborrhoeic Keratoses Induced by Oral Esomeprazole: A Coincidental Finding or Linked Pathogenesis?

Nilay Duman, Çiğdem Özdemir & Serap Polat · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Aim: Eruptive seborrhoeic keratoses are characterized by rapid onset of multiple seborrhoeic keratoses. They can be associated with internal malignancies, inflammatory dermatoses and drug reactions. Our aim was to present a case with eruptive seborrhoeic keratoses appeared during...

Open access Research Article 10.9734/JAMPS/2015/18850

Acute and Subacute Toxicological Assessment of the Leaf Aqueous Extract of Eremomastax speciosa (Acanthaceae) in Wistar Rats

Gaël Tchokomeni Siwe, George Enonchong Enow-Orock, André Perfusion Amang, Christophe Mezui, Alain Bertrand Dongmo & Paul Vernyuy Tan · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Aim: The present study was carried out to investigate the possible toxic effects of the leaf aqueous extract from Eremomastax speciosa and also to evaluate the acceptable safety level of this extract in Wistar rats. Place and Duration of Study: Department of Animal Biology and Ph...

Open access Research Article 10.9734/JAMPS/2015/18361

Ex vivo Antiplasmodial Activity of Plant Extracts Used in Traditional Medicine in Côte d’ivoire

K. D. Tano, W. Yavo, J. N. D. Trebissou, A. T. Offianan, M. T. Dable, A. M. Amiah, E. I. H. Menan & A. J. Djaman · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

In view of increased resistance of Plasmodium falciparum to almost all conventional antimalarial drugs, it has become necessary to search for new classes of molecules from traditional medicinal plants. Indeed, the best antimalarial drugs for which there are fewer cases of resista...

Open access Research Article 10.9734/JAMPS/2015/18138

Detection of Extended Spectrum β-Lactamase Producing Escherichia coli in Neonatal Unit of a Tertiary Health Institution, South-South Nigeria

I. O. Idang, A. E. Moses, A. N. Umo & E. E. Ikpeme · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Aims: To determine the prevalence of multidrug resistant (MDR) and Extended Spectrum β-lactamase producing (ESBL) E. coli in neonates, their mothers and healthcare workers (HCWs) in the neonatal wards of the University of Uyo Teaching Hospital (UUTH), Uyo-Nigeria. Study Design: I...

Open access Research Article 10.9734/JAMPS/2015/18742

Decreased Serum Magnesium Level among Nigerian Women with Late Onset Pre-eclampsia

F. N. Okoye, A. S. Anzaku, J. I. Chigbo, J. Musa & I. A. O. Ujah · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Background: Pre-eclampsia is a common medical complication of pregnancy associated with increased maternal and perinatal mortality and morbidity. Its etiology is unknown, although several evidences indicate that deficiency of various nutritional elements might play important role...

Open access Research Article 10.9734/JAMPS/2015/18500

A Comprehensive Review on Ethno-Medicine, Phytochemistry and Ethnopharmacology of Chrysophyllum albidum

J. O. T. Emudainohwo, E. O. Erhirhie, E. G. Moke & K. E. Edje · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Chrysophyllum albidum (Sapotaceae), commonly called white star apple is a very useful medicinal plant common in the tropical and sub-tropical regions of the world. This review is an update assemblage on the traditional, phytochemical and ethno-pharmacological studies carried out...

Open access Research Article 10.9734/JAMPS/2015/18641