The global Coronavirus disease 2019 (COVID-19) pandemic, caused by Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, has indeed seen the emergence of multiple variants. There are several direct-acting antiviral drugs that have been approved or are in process...
Open access
Research Article10.9734/jpri/2024/v36i97574
Aim: To overcome the logistical hurdles associated with cryostorage, cell therapy products would benefit from being stored as a (freeze-) dried product. However, there is currently unfortunately not a lot of focus in the field to evaluate formulations for their capabilities to pr...
Open access
Research Article10.9734/jpri/2024/v36i97573
This research examines the impact of the U.S. FDA's Regenerative Medicine Advanced Therapy (RMAT) designation on biotechnology and small pharmaceutical companies, focusing on both stock price reactions and drug development timelines. The research employs an event-study methodolog...
Open access
Research Article10.9734/jpri/2024/v36i97572
The growing interest in microsponge-based topical formulations compared to traditional ones is shaping the future of skincare and pharmaceutical treatments. Microsponges are gaining attention for their ability to enhance drug stability, control release, and target specific areas,...
Open access
Research Article10.9734/jpri/2024/v36i87571
We have undertaken to evaluate the pharmacological studies of Gymnema sylvestre using pharmacolical methods,disc diffusion, and anti-inflammatory methods. The Alkaloid, Carbohydrate, Protein,Resin, Saponin, and Glycosides were present whereas, steroid, flavanoid, and tannin were...
Open access
Research Article10.9734/jpri/2024/v36i87570
Chukwuma J. Okafor, Rodolfo Isidro Bosch Bayard, Diane Millo Martin, Salma Mahmoud, Said A. Yusuf, Minja T. Lilian, E N Adejumo, Nibras M. Hilal, Tarik A. Khamis, Asila M. Haji & Rayan J. Ali·Journal of Pharmaceutical Research International·2024
Background: Daily iron and folic acid supplementation (IFAS) during pregnancy reduces the risk of all types of maternal anaemia and iron deficiency anaemia at term; despite the WHO recommendations, pregnant women are still vulnerable because the use of Iron and Folic Acid Supple...
Open access
Research Article10.9734/jpri/2024/v36i87569
The development of a dengue vaccine presents numerous challenges, largely due to the complexity of the virus and the human immune response. One of the primary hurdles is Antibody-Dependent Enhancement (ADE), where antibodies from a previous dengue infection can facilitate a more...
Open access
Research Article10.9734/jpri/2024/v36i87567
Antibiotic resistance of microbial pathogens has become a threat to public health, with observed increase in outbreak of infections, therapeutic failure, morbidity and mortality. Pathogenic Escherichia coli and other extended spectrum beta lactamase (ESBL) producing bacteria caus...
Open access
Research Article10.9734/jpri/2024/v36i87568
The purpose of this work is to use the practical Emulsification Diffusion Method (EDM) to reduce the particle size to the nanometer range. The application of carefully engineered materials at this length scale to create new therapeutic and diagnostic modalities is the field of na...
Open access
Research Article10.9734/jpri/2024/v36i87566
Aims: To estimate the level of understanding of non-palliative physicians regarding the palliative approach and to identify areas of weakness in their management of advanced terminal symptoms. Study Design: An observational study was conducted among physicians at a single center...
Open access
Research Article10.9734/jpri/2024/v36i87564