There is no overemphasizing the need for novel phytotherapeutic agents to combat the menace of drug resistance in microbial pathogens. Many plant species so far, have yielded some bioactive compounds with great promise for such drugs. Trichilia heudelotii (Meliaceae) is commonly...
Open access
Research Article10.9734/jpri/2024/v36i37504
Background: The incidence of lung adenocarcinoma (LUAD) is increasing worldwide with different prognosis. Ephrin-A2（EFNA2), a member of the Eph/ephrin family, is associated with tumor progression. However, the correlations of EFNA2 with prognosis in LUAD remain unclear. The pu...
Open access
Research Article10.9734/jpri/2024/v36i37503
Introduction: Excessive menstrual bleeding is a common problem in reproductive age group females, and it is reported that 1 in 20 lifetime chances, a female needs consulting the physician for excessive and prolonged menstrual bleeding. Ayurvedic literature describes excessive men...
Open access
Research Article10.9734/jpri/2024/v36i37502
Sara Shahid, Zuha Tariq, Obeda Asghar, Arooj Majeed, Umair Amjad, Wasiq Ali, Ahmad Sarfaraz, Muhammad Ahmed Saeed, M.Sohaib Sultan Sabri, Mohammad Abdullah, Azwa Zaheer, Muhammad Aamir, Talha Rehman, Asfa Iqbal & Muhammad Zahid Iqbal·Journal of Pharmaceutical Research International·2024
Introduction: Chronic Obstructive Pulmonary Disease (COPD) is a respiratory disease characterized by restriction in expiratory airflow. It is among one of the major causes of illness and death globally. COPD causes severe negative effects on physical and mental health. It has a d...
Open access
Research Article10.9734/jpri/2024/v36i27501
Ramya Teja Medarametla, K. Venkata Gopaiah, J. N. Suresh Kumar, A. Kumar Sai, G. Mohana Chari, A. Kranti Kiran, B. Koteswarao Naik & K. Sandya Rani·Journal of Pharmaceutical Research International·2024
The primary objective of this main study is to develop and assess the sustained-release matrix tablets containing Valsartan, an angiotensin II receptor type 1 antagonist. The powder mixtures underwent a thorough examination of pre-compression parameters and observed angle of repo...
Open access
Research Article10.9734/jpri/2024/v36i27500
Prescriptions for medications have increased significantly over time. The primary reason for this growth has been the rise in demand for drugs that effectively treat age-related and chronic disorders. Additionally, other variables like health insurance companies and medical ads h...
Open access
Research Article10.9734/jpri/2024/v36i27499
Muhammad Abid Mustafa, Namra Rasheed, Hamza Farooq, Muntaha Fazal, Emaan Asif, Hamna Shafiq, Muqadas Amin, Gohar Jaan, Amna Nadeem, Tooba Farooq, Neha Fatima, Sadia Ahmad & Muhammad Zahid Iqbal·Journal of Pharmaceutical Research International·2024
Nanoemulsions are stable liquid-in-liquid dispersions with large surface areas, strong stability, optical transparency, and adaptable rheology. These submicron-sized emulsions are being studied for drug delivery and targeting in cosmetics, diagnostics, drug therapies, and biotech...
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Research Article10.9734/jpri/2024/v36i27498
Background: Drug metabolism is a crucial aspect of medical practice and pharmacology, involving the transformation of drugs by various bodily systems to create compounds that are more easily eliminated from the body. Sorafenib was reported as a useful adjuvant treatment in patien...
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Research Article10.9734/jpri/2024/v36i27497
Introduction: The liver is one of the principal organs of our body involved in over 500 physiological functions related to metabolism, digestion, immunity, and storage of nutrients, which makes it an essential organ to preserve life. The aim of my study is to measure the differen...
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Research Article10.9734/jpri/2024/v36i17496
Development of cheap and reliable diagnostics is pivotal in the control of infectious diseases. Currently, one of the best strategies to tackle infectious disease is the use of natural products from plant origin, due to the perception that long term use of western medicine induce...
Open access
Research Article10.9734/jpri/2024/v36i17495