Background: High dosage of lansoprazole (LPZ) can be used to control acidic microenvironment surrounding the cancerous cells thus improving tumor response. Aim: The study aimed at investigating the possible antitumor efficacy and safety of high dose of LPZ pretreatment in patient...
Open access
Research Article10.9734/jpri/2023/v35i177387
Background: The emergence of antimicrobial-resistant bacteria has become a public threat, creating a burden on medical care in hospitals. Carbapenem-resistant organisms are a source of both community-acquired and healthcare-acquired infection that poses a substantial hazard to pu...
Open access
Research Article10.9734/jpri/2023/v35i177386
The discovery of gravitational waves (GW) from the coalescence binary system reduces the mass-gap to (2.6 – 5) M⊙ . Hypothetical stars such as the super-Chandrasekhar mass white dwarf, quark star, boson star, electro weak star, grav-star, dark matter star , supermassive neutron s...
This article aims to provide a concise overview of the existing literature on Sturge-Weber syndrome in infants. This comprehensive review presents key information regarding the prevalence, clinical characteristics, diagnostic methods, and available treatments based on recent glob...
Open access
Research Article10.9734/jpri/2023/v35i167384
Background: Ideal requirement of an intracanal medicament is that it should have an antibacterial action for the success of endodontic procedures. The "golden standard" intracanal medication is calcium hydroxide, but it still has drawbacks like internal root resorption. The searc...
Open access
Research Article10.9734/jpri/2023/v35i177385
Various medications are available to treat stress and depression, but there is a growing interest in plant-based drugs due to their effectiveness and minimal side effects. As a result, researchers conducted a study to evaluate the adaptogenic and antidepressant effects of extract...
Open access
Research Article10.9734/jpri/2023/v35i167383
Aim: Polycystic ovary syndrome (PCOS) is a common endocrine disorder. The aim of the present study is to evaluate the effects of the oral administration of Coscinium fenestratum bark extract in letrozole-induced PCOS in rats. Methods: Thirty female Sprague-Dawley (SD) rats were r...
Open access
Research Article10.9734/jpri/2023/v35i167381
Hossein Mostafa Elbadawy, Amin Khaled Khattab, Fahad Dakilallah Aljohani, Mekky Abouzied, Mohannad A. Bahlaq, Khalid Abdelkarim Abdalla, Sultan Hamid M. Aljohani, Heba M. Eltahir, Rania K. Alharbi, Talal Aljumaidi, Muayad Albadrani, Mohannad A. Almikhlafi & Ahmed Aldhafiri·Journal of Pharmaceutical Research International·2023
Background: SARS-CoV-2 infections emerged in China and spread globally causing the Corona virus disease 2019 (COVID19) pandemic. Dispersed reports from different countries reported the possibility of the incidence of SARS-CoV-2 reinfection in individual reported cases. The aim of...
Open access
Research Article10.9734/jpri/2023/v35i167382
Syed Zahid Shah, Raja Taha Yaseen Khan, Sandeep Kumar, Nasir Mehmood, Muhammad Usman Naeem, Hina Ismail, Saleem Shahzad, Muhammad Ali Khalid, Ghulamullah Lail, Muhammad Adeel, Ghazi Abrar, Muhammad Qaiser Panezai, Vijesh Kumar, Danish Kumar, Abdullah Nasir, Mahboob Jan, Nasir Hasan Luck & Abdul Haseeb Memon·Journal of Pharmaceutical Research International·2023
Introduction: Most of the lactate in the body is cleared in the liver. Tissue hypoxia results in increased production of lactate and decreased utility of it. Hepatic insult results not only an increase in the blood lactate levels but also is an independent prognostic marker in cr...
Open access
Research Article10.9734/jpri/2023/v35i167380
Bandar A. Suliman, Ahmed Aljuhani, Zuhur Ramadan Almohammadi, Yasser A. Abdou, Sultan Saud Alahmadi, Amin Khattab, Mohannad Almikhlafi & Hossein M. Elbadawy·Journal of Pharmaceutical Research International·2023
Background: Rapid and accurate diagnosis of COVID-19 is critical for the management of patients and to limit the spread of the infection. real-time reverse transcription polymerase chain reaction (RT- PCR) is the gold standard for the diagnosis of SARS-CoV-2 infection, however, i...
Open access
Research Article10.9734/jpri/2023/v35i157379