Background: Apremilast is an oral, selective phosphodiesterase-4 (PDE-4) enzyme inhibitor, approved by the US-FDA for management of moderate to severe plaque psoriasis. Apremilast belongs to class of drug that function by modulating pro-inflammatory cytokines and have a low molec...
Open access
Research Article10.9734/jpri/2022/v34i43B36316
Introduction: Numerous obesity indices have been developed that predict non-alcoholic fatty liver disease (NAFLD). We in our study aimed at evaluating a few of these tools including waist to height ratio (WHtR), waist circumferences (WC), body mass index (BMI) and fatty liver ind...
Open access
Research Article10.9734/jpri/2022/v34i43B36318
Hanoof Alqhatani, Mohammed S. Aldalham Alqahtani, Faris A. Alasmre, Khaled Abdulwahab Amer, Abdulrahman Ali Aldosari, Basel Mohammed Saleh Althubait, Abdulrahman Abdullah Mofreh Al Mudawi & Mushary Saeed A. Alqahtani·Journal of Pharmaceutical Research International·2022
Background: By the end of 2019, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was diagnosed in Wuhan, Hubei province, China. In Saudi Arabia, the government applied prompt preventive measures against coronavirus disease 19 (COVID-19). COVID-19 associated restrict...
Open access
Research Article10.9734/jpri/2022/v34i43B36319
Aims: C. spinosa (Family Rubiaceae) is a valuable medicinal since years ago. A protocol was developed including best sterilization and best medium for callus induction of C. spinosa using leaf discs as explants. Methodology: Sterilization protocol optimized using different concen...
Open access
Research Article10.9734/jpri/2022/v34i43A36313
Background: Benzimidazoles are aromatic, heterocyclic organic molecules which exhibit pharmacological potential as anti-inflammatory, antiulcer, anti-hypertensive, anticancer agent, and anthelmintic treatments. The benzimidazoles could inhibit human hexokinase II, which is a crit...
Open access
Research Article10.9734/jpri/2022/v34i43A36311
Background: Epidural anesthesia is a perioperative pain control treatment that has a variety of applications in anaesthesiology. It could be used as as a primary anaesthetic, although it's most usually utilised as an adjuvant for management of pain. It could be a one-time shot o...
Open access
Research Article10.9734/jpri/2022/v34i43A36310
Introduction: Dental caries is a bacterial illness that causes localized disintegration and loss of calcified components in the teeth. Different plant extracts have been used to assess the anti-bacterial activity against the pathogens known to induced dental caries. Objective: Th...
Open access
Research Article10.9734/jpri/2022/v34i43A36307
Aim: This study aims to find out the incidence of atrial fibrillation new onset in STEMI patients receiving primary PCI Sample: A total of 169 patients have included after sample size calculation by using WHO sample size calculator version 2.0. Study Design: Descriptive cross-sec...
Open access
Research Article10.9734/jpri/2022/v34i43A36308
Seriphidium kurramenses traditionally medicinal plant usually not present in Pakistan is used in different biological activities to cure various ailments. However, scare studies are present on S. kurramenses regarding to its medicinal importance to treat fever, inflammation and p...
Open access
Research Article10.9734/jpri/2022/v34i43A36309
Aim: The study analysed the bioactive compounds (BACs) present in aqueous ethanol, dichloromethane, and n-hexane extracts of pumpkin (Cucurbita pepo) using Gas chromatography–mass spectrometry (GC-MS) technique. Methodology: The dried grounded seed C. pepo were successively extra...
Open access
Research Article10.9734/jpri/2022/v34i43A36305