Deva Tulasi Komatineni, Udaya Ratna Kolli, Mohammed Bashir Abazar Elmamoon Ball Elsheep, Varshitha Reddy Balineni, Keerthi Sri Gundla, Yousif Osman Salih Saeed, Jithendra Chimakurthy & Ravindra Babu Pingili·Journal of Pharmaceutical Research International·2022
An antidote is a therapeutic agent that counteracts the hazardous effects of a medicine or toxin, according to the International Programmed of Chemical Safety. Antidotes have been defined as agents that alter the poisonous substance's kinetics or interfere with its impact at rece...
Open access
Research Article10.9734/jpri/2022/v34i38B36228
Fedratinib (INREBIC®) is a JAK2-selective inhibitor that has been developed as an oral treatment for myelofibrosis. It was approved for the first time in the United States in August 2019 to treat adult patients with intermediate-2 or high-risk primary or secondary (post-polycytha...
Open access
Research Article10.9734/jpri/2022/v34i38B36226
Aim: To investigate the prevalence of meningitis in neonatal sepsis patients at a tertiary care hospital. Study Design: A cross-sectional study. Place and Duration: Department of pediatrics, Civil Hospital Karachi from 11 – 2019 to 04 – 2020. Methodology: A total of 120 Neonates...
Open access
Research Article10.9734/jpri/2022/v34i38B36227
Currently, little is known about the effects of e-cigarette use on chronic respiratory diseases, due to their relative novelty. This review compiles data on the cellular effects of e-cigarette use with population data on disease incidence to determine potential risk for COPD and...
Open access
Research Article10.9734/jpri/2022/v34i38B36225
Vaccines are one of the most significant achievements of science and public health for prevention of infectious disease. Overall vaccination policies for HCP in should be periodically revaluated in order to provide optimal protection against vaccine preventable diseases and infec...
Open access
Research Article10.9734/jpri/2022/v34i38B36224
Background: Letrozole, a commonly prescribed Neoadjuvant endocrine therapeutic drug in hormone receptor positive breast cancer females, causes osteoporosis along with several other debilitating effects. The objective of this study was to observe the changes in trabecular diameter...
Open access
Research Article10.9734/jpri/2022/v34i38B36223
Objective: The study was done to evaluate the average time taken by the operators to apply the rubber dam, procedure time and the acceptability or rejection of placement of rubber dam by the patients during endodontic treatment procedures. Design: The study was carried out on 450...
Open access
Research Article10.9734/jpri/2022/v34i38B36222
Objective: Thiamine or vitamin B1 is a fundamental vitamins and minerals and enzyme cofactor that are needed for most of the anabolic and catabolic reaction that occurs in organisms. Deficiency of Thiamine has been associated with numerous complications in diabetes mellitus (DM)...
Open access
Research Article10.9734/jpri/2022/v34i38A36218
Objectives: To study the sociodemographic and clinical patterns of thyroid lesions in Sindh, Pakistan. Methodology: A prospective observational study was conducted at the department of Surgery, Ward - 26, Jinnah Postgraduate Medical Centre, Karachi between March 2018 to 2020. All...
Open access
Research Article10.9734/jpri/2022/v34i38A36219
Aim: Measurement of serial serum lactate levels in patients presenting with sepsis and correlating with 1. early lactate clearance with mortality. 2. Early lactate clearance vs. first (baseline) lactate level in mortality prediction. 3. Early lactate clearance vs. ACUTE PHYSIOL...
Open access
Research Article10.9734/jpri/2022/v34i38A36220