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Research Article Open access CC BY 4.0

A Rare Case Report of Duodenal Marginal Zone B-cell Lymphoma Related to Immunoproliferative Small Intestinal Disease and Associated Lymphoma (IPSID)

Ziad Aljarad, Mahmoud Nasser, Ahmad Ghazal, Mamdouh Alkhaled, Batol Obeed, M. Malek Shaghaleh, M. Wafa Hamoud Alhussein

Journal of Advances in Medicine and Medical Research · pp. 1–4 · Published 30 Mar 2017

10.9734/BJMMR/2017/32496

Abstract

Marginal zone B-cell lymphoma is a unique lymphoma of the gastrointestinal tract most commonly in developing countries with poor socioeconomic conditions, poor hygiene, malnutrition, and a high degree of intestinal infections where IPSID is common. We experienced a rare case of extranodal MZBCL in duodenum (sub type of MALT) in a 14-year-old girl who complained of epigastric pain. Abdominal Computed Tomography (CT) with Intravenous (IV) contrast showed mixed mass infiltrate the intestinal wall with mesenteric lymphadenopathy. Upper gastrointestinal tract endoscopy had showed obstruction in the 2nd segment of duodenum, biopsies were taken. Pathology report according to findings refers to immunoproliferative small intestinal disease and associated lymphoma (IPSID) and by immunostains, cells features are compatible with extranodal marginal zone B cell lymphoma which is sub type of MALT lymphoma.

Duodenum IPSID marginal zone B-cell lymphoma gastrointestinal tract lymphoma.

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