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An Evaluation of Hepato-protective Activity of Ethanolic Extract of Solanum nigrum with Varying Doses on CCL4 Induced Hepatic Injured Rat

Humayra Zaman Himi, Md.Mahbubur Rahman, Syed Abir Hasan, Lia Rose Merry D. Cruze, Syeda Taarin Ishraat, Md. Mustafiz Chowdhury

Asian Journal of Advanced Research and Reports · pp. 75–80 · Published 16 Mar 2024

10.9734/ajarr/2024/v18i4625

Abstract

Herbal medicine, an art form as well as a profession, is the use of herbs and herbal remedies to prevent, treat, or cure sickness. In certain tribes, herbal medicine is also known as herbal remedies. In this investigation, rats were used in the research to examine the lipid profiles of the extract from Solanum nigrum. In the case of SGPT, group 6 showed statistically significant outcomes (p< 0.05), whereas in the case of SGOT, both groups 5 and 6 showed statistically significant outcomes (p< 0.05). In relation to the SGPT and the SGOT, this is being said. Both group 5 and group 6 showed statistically significant amounts of creatinine and urea (p< 0.05) during the renal function test. Group 6 with a dose of 1200 mg/kg showed statistically significant results for high-density lipoprotein (HDL) and low-density lipoprotein (LDL) (p< 0.05). Furthermore, at dosages of 600 mg/kg and 1200 mg/kg, respectively, the triglyceride level in groups 5 and 6 was statistically significant (p< 0.05). There were no results that were deemed statistically significant for total cholesterol.

Herbal medicine Solanum nigrum HDL LDL phytochemicals herbal medicine triglyceride landular organ

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