Antioxidant Studies of Thiazole Ring Bearing Chalcone Derivatives
Ashok Babu Kasetti, Jayesh Dwivedi, Ravindra Nagasuri
Journal of Pharmaceutical Research International · pp. 355–359 · Published 16 Dec 2021
10.9734/jpri/2021/v33i59A34280Abstract
Oxidative stress is one of the common problems seen in a variety of diseases. Chalcones and in particular heteroaryl chalcones had reported with promising antioxidant activities. Hence, in the present work, we reported the antioxidant activity of twenty thiazole ring bearing chalcone derivatives (1-20). Among the tested compounds, compounds 17, 19 and 20 containing 2-pyridinyl, 3-pyridinyl and 2-thiazolyl scaffolds showed superior antioxidant activity than the standard with their IC50 values 4±1µg/mL, 3±1 µg/mL and 5±1 µg/mL respectively. The compound 19 is an interesting lead for the development of newer antioxidant agents.
Cited by 2
Kibrom Mezgebe, Yadessa Melaku, Endale Mulugeta · ACS Omega · 2023
Showing 1 of 2 known citations — external sources report more than can currently be individually listed.
Related research
- Salivary Lipid Peroxidation and Antioxidant Status in Nigerian Cigarette Smokers with or Without Periodontitis — shares topic coverage
- Profile of Biochemical and Oxidative Stress Markers in Male Athletes Following Strenuous Exercise Session — shares topic coverage
- Atherogenicity, Oxidative Stress, Heavy Metals and Bioelements Status in Hypertensive Nigerians in an Urban Population — shares topic coverage
- Oxidative Stress Biomarkers (Malondialdehyde, Superoxide Dismutase, and Catalase) as Predictors of Cardiovascular Disease Risk: A Review — shares topic coverage
- Ebselen a Seleno-organic Molecule Inhibits Alteration in the Biological Responses in Hypoxic Human Alveolar Lung Epithelial Cells — shares topic coverage
Article metrics
Real usage data collected on this platform.
4
Page views
0
PDF downloads
0
Outbound clicks
2
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.