Causes of Dysnatremia in Cancer Patients: A Review
Daniela Rădulescu, Ileana Adela Văcăroiu, Flavia Liliana Turcu, Carmen Bogeanu
Journal of Pharmaceutical Research International · pp. 6–13 · Published 3 Jun 2022
10.9734/jpri/2022/v34i40A36251Abstract
Dysnatremias occur with high incidence in cancer patients and have negative impact on quality of life, survival, hospitalization length. Both cancer and its therapy are responsible; coexisting comorbidities may also be involved. Hyponatremia is the most common electrolyte disorder and is usually multifactorial. Hypernatremia, although more rare, is associated with poorer outcome. Diagnosis of true dysnatremias may be a challenge in patients with active cancer, as they must be often differentiated from spurious dysnatremias. Assessing the extracellular volume is the first step for establishing the cause of a dysnatremia; as such hypovolemic, euvolemic and hypervolemic dysnatremias have distinct etiology. The present article briefly reviews cancer-specific and treatment-specific causes of dysnatremias.
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