Clinical Characteristics and Pathophysiological Features of Restless Legs Syndrome (RLS): Recent Advances and Future Challenges
Journal of Advances in Medicine and Medical Research · pp. 1470–1483 · Published 15 Nov 2014
10.9734/BJMMR/2015/14009Abstract
Restless Legs Syndrome (RLS)/Willi’s-Ekbom disease (WED) or Jimmy Legs is a neurological sensory-motor disorder that causes intense restlessness and unpleasant creepy-crawly feelings inside the lower legs at rest. It can be primary (idiopathic) or secondary (symptomatic) and affects 7-10% of general population with a significant female predominance. RLS is generally associated with conditions like iron deficiency, low serum ferritin levels, pregnancy, menopause, chronic renal disease, diabetes mellitus, cardiovascular disease, Parkinson’s disease and rheumatoid arthritis etc, however, the relationship is not completely understood. In this review, I discussed recent developments on epidemiology, etiology, pathogenesis, diagnosis and clinical management of RLS.
Cited by 2
Carlos L. Rodriguez, Nancy Foldvary-Schaefer · Neuro-Geriatrics · 2017
Showing 1 of 2 known citations — external sources report more than can currently be individually listed.
Related research
- Smoking Effects of Marijuana and Cigarette on Blood Chemistry, Hematology and Plasma Dopamine Levels in Young Adults — shares topic coverage
- Biochemical Characterization of Two Polyphenol Oxidase Purified from Edible Yam (Dioscorea cayenensis-rotundata cv. Kponan) Cultivated in Côte d’Ivoire — shares topic coverage
- Isolation of a Latent Polyphenol Oxidase from Edible Yam (Dioscorea cayenensis-rotundata cv. Zrèzrou) Cultivated in Côte D’ivoire — shares topic coverage
- L-Phenylalanine and L-Tyrosine Catabolism by Thermophilic Geobacillus stearothermophilus — shares topic coverage
- Ameliorative Effect of Hydromethanolic Fraction of Citrullus lanatus Seeds on Biochemical and Histology Parameters of Female Wistar Rats Administered with Caffeine — shares topic coverage
Article metrics
Real usage data collected on this platform.
3
Page views
0
PDF downloads
3
Outbound clicks
2
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.