Comparative Antibacterial Activity of Honey and Gentamicin against Klebsiella Species
O. S. Dauda, A. S. Ohunayo, A. T. Afolabi, O. J. John-Mese, O. E. Adeleke
Journal of Advances in Biology & Biotechnology · pp. 28–34 · Published 17 Nov 2022
10.9734/jabb/2022/v25i8591Abstract
Klebsiella species are one of the major causes of systematic infections, theses gram negative organisms are also capable of housing various resistant genes to resist the potency of conventional antibiotics. These observations account for the need to assess the antibacterial activity of Gentamicin and natural products against Klebsiella. A total of fifty (50) clinical isolates of Klebsiella species of different pathological sources were collected from four different Teaching Hospitals in Southwest, Nigeria. The identification of all the isolates was done using conventional biochemical tests. Antibiogram was carried out on all 50 Klebsiella clinical isolates using multiple antibiotic discs and the sensitivity of honey was done using the agar diffusion method. In the antimicrobial susceptibility test on honey, two undiluted different samples of honey (Honey A Refined and Honey B Natural) showed high activity and 1:2 to 1:6 aq. dilutions showed less activity against the Klebsiella isolates. Gentamicin used at the concentration of 4.0µg/ml has great activity against the isolates but was basically lower than the antibacterial activity of each undiluted honey. In the occasion of therapeutic disaster with gentamicin or any other associated antibiotics, honey offers an appropriate and improved alternative in dealing with infected burn wounds and other infections like urinary tract infections, nosocomial infections, etc.
References (15)
- 1 Antibiotics and Bacterial Resistance in the 21st Century [DOI]
- 2 Honey: its medicinal property and antibacterial activity [DOI]
- 3 Honey and Health: A Review of Recent Clinical Research. [DOI]
- 4 The antibacterial activities of honey [DOI]
- 5 Activity of Specialized Biomolecules against Gram-Positive and Gram-Negative Bacteria [DOI]
- 6 Evidence for Clinical Use of Honey in Wound Healing as an Anti-bacterial, Anti-inflammatory Anti-oxidant and Anti-viral Agent: A Review [DOI]
- 7 Salmonella, Shigella, and Yersinia [DOI]
- 8 Fighting Antibiotic Resistance in Hospital-Acquired Infections: Current State and Emerging Technologies in Disease Prevention, Diagnostics and Therapy [DOI]
- 9 Honey: Another Alternative in the Fight against Antibiotic-Resistant Bacteria? [DOI]
- 10 Antimicrobial Properties on Non-Antibiotic Drugs in the Era of Increased Bacterial Resistance [DOI]
- 11 Determination of the botanical origin of honeybee honeys based on the analysis of their selected physicochemical parameters coupled with chemometric assays [DOI]
- 12 Antibacterial Efficacy of Raw and Processed Honey [DOI]
- 13 Comparison of the Antimicrobial Activities of Four Honeys From Three Countries (New Zealand, Cuba, and Kenya) [DOI]
- 14 Comparative antibacterial activity of honey and gentamicin against Escherichia coli and pseudomonas aeruginosa.
- 15 Detection of a gentamicin-resistant burn wound strain of pseudomonas aeruginosa but sensitive to honey and garcinia kola (heckel) seed extract.
Cited by 3
A. O. Ogunniran, O. S. Dauda, D. Rotimi · Toxicology Reports · 2024
A. Abd, Ali Alrifai, Ammar K. Jasman · Microbial Bioactives · 2024
Showing 2 of 3 known citations — external sources report more than can currently be individually listed.
Related research
- The Ameliorative Effect of Honey on Lead (Pb) – Induced Nephrotoxicity in Male Wistar Rats — shares topic coverage
- A Randomized Trial of Honey Versus Povidone Iodine Dressings: Pain Profile of Wagner Grade 2 Diabetic Foot Ulcers — shares topic coverage
- Preliminary Detection of Bacillus species in Commercial Honey — shares topic coverage
- Synergistic Effect of Monofloral Honeys and Essential Oils against Pseudomonas aeruginosa — shares topic coverage
- Physiochemical Parameters of Stored Honey Samples and Their Combined Effect with Antibiotics on Clinical Isolates — shares topic coverage
Article metrics
Real usage data collected on this platform.
39
Page views
0
PDF downloads
17
Outbound clicks
3
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.