Comparative Study on Hair Transplantation with or without Platelets Rich Plasma Effect in Treatment of Cicatricial Alopecia

Abstract

Background and Aim: Scarring is an important clinical problem that occurs because of skin damage. Each year, around 100 million individuals in the Western world develop new scars, some of which pose substantial issues for those who are affected. The purpose of this work was to compare the effect of platelets rich plasma (PRP) on hair transplantation in treatment of cicatricial alopecia Methods: This randomized control study was performed on 45 cases with 2ry cicatricial alopecia. The alopecic area of each patient was divided into two halves: 1st half (A) [hair transplantation without PRP injection] and 2nd half (B) [hair transplantation after intradermal injection of autologous PRP in recipient site intra-operative and two weeks postoperative]. Each patient was submitted to general examination, local examination of the donor and recipient sites, and laboratory investigations. Results: Our study suggests that it after hair transplantation is an effective treatment for cicatricial alopecia (CA). Conclusion: PRP has a high concentration of growth factors such as platelet-derived growth factor, vascular endothelial growth factor, and epidermal growth factor. Our study suggests that PRP is an effective treatment for CA.