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Research Article Open access CC BY 3.0

Cost Effectiveness of Intermittent Preventive Treatment of Malaria in Infants in Ghana

Anselm Komla Abotsi, Ebenezer Inkoom, Eric Ribaira, Rozenn Le Mentec, Pierre Lévy, Herve Lafarge, Alexandra de Sousa

International Journal of TROPICAL DISEASE & Health · pp. 1–15 · Published 29 Feb 2012

10.9734/IJTDH/2012/1017

Abstract

Aim: In order to integrate malaria Intermittent Preventive Treatment in infants (IPTi) into the Ghana national immunization programme, there was the need to evaluate the feasibility of IPTi by assessing the intervention operational issues including its implementation costs, and its cost effectiveness. Study Design: Cross-sectional study. Place and Duration of Study: Upper East Region, Ghana, between July 2007 and July 2009 Methods: We calculated the costs of administrating IPTi during vaccination sessions; the costs of programme implementation during the first year of implementation (start-up costs) and in routine years (recurrent costs). For the purposes of cost-effectiveness analysis, all economic costs (including financial and opportunity costs) and the net cost were estimated. To estimate the cost effectiveness ratios of IPTi, the aggregate cost of providing the intervention for a reference target population of 1,000 infants was divided by its health outcome. Sensitivity analyses were carried out to understand the results robustness. Results: IPTi gross costs in start up and in routine years were estimated at 70.66 cents and 29.72 cents per dose, or $2.0 and $0.87 per infant, respectively. The gross cost per DALY saved was estimated at $3.49 and the net cost of IPTi for 1,000 infants was $-3,416.38 in the routine years rending IPTi a highly cost saving intervention. Sensitivity analyses showed that the cost per DALY saved never went up more than $4.50 maintaining the intervention still highly cost effective. Conclusion: IPTi in Ghana is a highly and robust cost effective intervention. The intervention is cost-saving and should be scaled up nationally to save children’s health and economic capital.

Malaria intermittent preventive treatment in infants health outcome direct delivery cost indirect delivery cost economic cost incremental costs cost effectiveness analysis

References (9)

  1. 1 The global burden of disease: a comprehensive assessment of mortality and disability from diseases injuries and risk factors in 1990 and projected to 2020.
  2. 2 Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trials [DOI]
  3. 3 Cluster randomised trial of intermittent preventive treatment for malaria in infants in area of high, seasonal transmission in Ghana [DOI]
  4. 4 Cost-effectiveness of malaria internittent preventive treatment in infants (IPTi) in Mozambique and the United Republic of Tanzania [DOI]
  5. 5 THE COST-EFFECTIVENESS OF PERMETHRIN-TREATED BED NETS IN AN AREA OF INTENSE MALARIA TRANSMISSION IN WESTERN KENYA [DOI]
  6. 6 From strategy development to routine implementation: the cost of Intermittent Preventive Treatment in Infants for malaria control [DOI]
  7. 7 Implementing intermittent preventive treatment in infants [DOI]
  8. 8 Intermittent Preventive Antimalarial Treatment in Infants [DOI]
  9. 9 Burden of Disease New South Wales - Feasibility Report [DOI]

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