Emerging Concepts of Megakaryocytes Distribution and Role in Inflammatory Joint Disease
Journal of Advances in Medicine and Medical Research · pp. 1–13 · Published 1 Nov 2018
10.9734/JAMMR/2018/44795Abstract
Inflammatory joint diseases are characterised by significant bone and cartilage destruction, leading to disability and reduced life quality. Some of these illnesses have a systemic character which leads to life-threatening conditions. The exact mechanisms that are involved in joint pathology are still not yet known, as a variety of cell types are implicated in them. Increasing evidence shows that megakaryocytes and platelets are key players in joint inflammation and bone remodeling, and in the accompanying systemic disorders such as thrombocytosis. Here we summarise the available data on the megakaryopoiesis, megakaryocyte distribution and discuss some aspects of their involvement in inflammatory joint diseases.
Cited by 0
No indexed citations yet.
Related research
- Physiological Reaction of Erythrocytes’ Micro Rheological Peculiarities in Milk Fed Piglets after the Negative Impact of the Environment — shares topic coverage
- Erythrocytes’ Microrheological Features of Piglets during the Phase of Dairy-vegetable Nutrition after Damage or Common Supercooling — shares topic coverage
- Erosive Cervico-occipital Arthritis Caused by Enthesitis in a Patient with Axial Spondylathritis — shares topic coverage
- Profiling Bioactive Compounds in the Bark of Cinchona officinalis L. and Anti-arthritic Properties Thereof — shares topic coverage
- Refinement of the Collagen Induced Arthritis Model in Rats by Infrared Thermography — shares topic coverage
Article metrics
Real usage data collected on this platform.
28
Page views
0
PDF downloads
7
Outbound clicks
0
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.