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Research Article Open access CC BY 4.0

Ethnobotany, Phytochemistry and Pharmacology of Pericopsis laxiflora (Baker) Meeuwen (Leguminosae) – A Review

Frederick Sarfo-Antwi, Christopher Larbie, Benjamin Obukowho Emikpe, Regina Appiah–Opong

International Journal of Biochemistry Research & Review · pp. 1–7 · Published 11 May 2021

10.9734/ijbcrr/2021/v30i230248

Abstract

Pericopsis laxiflora (Family Leguminosae) is a medicinal plant that is ubiquitous especially in the tropical and savannah regions. There are many reports on folkloric and traditional medicinal uses that include haemorrhoids, rheumatism, abdominal pain treatment, diarrhoea, and dysentery, fever, skin diseases and jaundice. Peer-reviewed articles were gathered by consulting the databases of Scopus, Medline, Web of Science, PubMed, Science Direct and Google Scholar. Phytochemical investigations have revealed many bioactive compounds such as β-carboline derivative and tryptamine derivative. The plant has been examined on the basis of the in vitro, in vivo or clinical evaluations and shown to possess major pharmacological activities. These include anti-trypanosomal, antimicrobial, antibacterial, antioxidant and anti-malarial activities. In the present review, an attempt has been made to congregate the traditional, phytochemical and pharmacological studies performed on Pericopsis laxiflora. Comprehensive safety and efficacy studies must be conducted on the plant. Generally, there are knowledge gaps that must be filled. Thus this review is intended for practitioners and researchers in the fields of ethnopharmacology, natural product chemistry and drug discovery related research.

Ethnobotany Pericopsis laxiflora pharmacology phytochemistry

References (5)

  1. 1 The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety [DOI]
  2. 2 African traditional medicine A dictionary of plant use and applications
  3. 3 Ethnobotanical study of some Ghanaian anti-malarial plants [DOI]
  4. 4 Comparative foliar epidermal studies of genus Pericopsis (Papilionaceae) in Nigeria
  5. 5 Phytochemical And Antimicrobial Properties Of The Genus Pericopsis Thwaites (Papilionaceae) In Nigeria

Cited by 6

Pericopsis laxiflora (Baker) stem bark extract is protective against carbon tetrachloride-induced acute liver damage by modulation of oxidative stress and inflammation

Frederick Sarfo-Antwi, Christopher Larbie, Benjamin Obukowho Emikpe · Journal of Taibah University for Science · 2024

Hydroethanolic extract and fractions of Pericopsis laxiflora stem bark protect against liver injury in Rat

Frederick Sarfo-Antwi, Christopher Larbie, Benjamin Obukowho Emikpe · Scientific African · 2024

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