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Research Article Open access CC BY 3.0

Haematological Values at Moderate Altitude in a Low-Income Population

Jean Bosco Gahutu

International Blood Research & Reviews · pp. 22–28 · Published 27 Jun 2013

10.9734/IBRR/2013/3530

Abstract

Aim: To illustrate haematological adaptation to moderate altitude in Rwanda. Study Design: A population-based cross-sectional study. Place and Duration of Study: The study was carried out at moderate altitude (1,649-1,768 m) among students of the National University of Rwanda and blood donors from Buhanda, Ruhango and Nyaruteja centres, from August to December 2011. Methods: Healthy volunteers (238 males and 106 females, age range: 18-40 years) were recruited in the study. Complete blood count was performed on a Coulter AcT 5diff and for some samples on a Sysmex KX-21N automated haematology analyzer. Results: Results (mean ± SD) were: erythrocyte count: males: 5.28 ± 0.53 X 1012/L, females: 4.72 ± 0.63 X 1012/L; haemoglobin concentration: males: 160 ± 16 g/L, females: 140 ± 18 g/L; haematocrit: males: 45 ± 4 %, females: 40 ± 5 %. The differential leukocyte count showed eosinophilia (4%) and increased lymphocytes (44%). Conclusion: The values for erythrocyte count, haemoglobin concentration, haematocrit, erythrocyte indices and leukocyte count are comparable to sea level values. The fact that haemoglobin concentration is not low as is the case in low-income populations living at sea level can be attributed to adaptation to moderate altitude.  

Moderate altitude haematology Rwanda

References (25)

  1. 1 Case 34-1990 [DOI]
  2. 2 Normal Reference Laboratory Values [DOI]
  3. 3 Andean, Tibetan, and Ethiopian patterns of adaptation to high-altitude hypoxia [DOI]
  4. 4 Genetic adaptation to high altitude in the Ethiopian highlands [DOI]
  5. 5 An Ethiopian pattern of human adaptation to high-altitude hypoxia [DOI]
  6. 6 Population-Based Hematologic and Immunologic Reference Values for a Healthy Ugandan Population [DOI]
  7. 7 High Altitude Adaptation in Tibetans [DOI]
  8. 8 Immunohaematological reference values in human immunodeficiency virus-negative adolescent and adults in rural northern Tanzania [DOI]
  9. 9 CLSI-Derived Hematology and Biochemistry Reference Intervals for Healthy Adults in Eastern and Southern Africa [DOI]
  10. 10 Genetic determinants of Tibetan high-altitude adaptation [DOI]
  11. 11 Hematological Parameters in High Altitude Residents Living at 4355, 4660, and 5500 Meters Above Sea Level [DOI]
  12. 12 Genetic Variants in EPAS1 Contribute to Adaptation to High-Altitude Hypoxia in Sherpas [DOI]
  13. 13 Haematological and Biochemical Reference Values for Healthy Adults in the Middle Belt of Ghana [DOI]
  14. 14 Laboratory reference values for healthy adults from southern Tanzania [DOI]
  15. 15 Reference Ranges for the Clinical Laboratory Derived from a Rural Population in Kericho, Kenya [DOI]
  16. 16 Reference Intervals in Healthy Adult Ugandan Blood Donors and Their Impact on Conducting International Vaccine Trials [DOI]
  17. 17 Population-Based Biochemistry, Immunologic and Hematological Reference Values for Adolescents and Young Adults in a Rural Population in Western Kenya [DOI]
  18. 18 Genetic approaches to understanding human adaptation to altitude in the Andes [DOI]
  19. 19 Hematological and Lipid Profile Changes in Sea-Level Natives after Exposure to 3550-m Altitude for 8 Months [DOI]
  20. 20 Hematological Reference Values for Healthy Adults in Togo [DOI]
  21. 21 Erythropoietin regulations in humans under different environmental and experimental conditions [DOI]
  22. 22 Ethnic variation in certain hematological and biochemical reference intervals in a south Indian healthy adult population [DOI]
  23. 23 Normal Hematological Values for Healthy Persons Living at 4000 Meters in Bolivia [DOI]
  24. 24 Hematological and Physiological Adaptations Following 46 Weeks of Moderate Altitude Residence [DOI]
  25. 25 A Rwandan altitude blood gas, acid-base and hemoglobin study [DOI]

Cited by 2

Complete blood count reference intervals from a healthy adult urban population in Kenya

Geoffrey Omuse, Daniel Maina, Jane Mwangi · PLOS ONE · 2018

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