Haemoassessment of Dogs Experimentally Infected with Single and Conjunct Trypanosoma congolense and Ancylostoma caninum and Treatment with Diminazene Aceturate and Mebendazole
Journal of Advances in Medicine and Medical Research · pp. 1–11 · Published 2 Mar 2016
10.9734/BJMMR/2016/24067Abstract
The haemoassessment of dogs with single Trypanosoma congolense (T. congolense) and conjunct T. congolense /A. caninum was determined in this study. Twelve mongrels of both sexes weighing between 4 to 8 kg were grouped into 3 of 4 members each. The group i (GPI) was the uninfected (control), group ii (GPII) was infected with T. congolense and group iii (GPIII) was conjunct infection of T. congolense/A. caninum. Post acclimatization GPIII was infected with 200 infective L3 of A. caninum, 2 weeks later both GPII and GPIII were given 2.5x106 trypanosomes intraperitoneally. Three weeks post trypanosome infection, treatment was done with 100 mg of mebendazole twice daily for 3 days and 7 mg/kg of diminazene aceturate. Result showed a significant decrease (p<0.05) in PCV, Hb and Rbc of both GPII and GPIII. The decrease in GPIII was more compared to that in GPII. There was significant decrease (p<0.05) in neutrophil, monocyte, lymphocyte and eosinophil counts of both GPII and GPIII except in basophil count which showed no significant difference (p<0.05) from GPI (control) throughout the experiment. Treatment with both diminazene aceturate and mebendazole cause significant haematological improvement.
References (28)
- 1 Trypanosoma brucei: A rapid “matching” method for estimating the host's parasitemia [DOI]
- 2 Human Hookworm Infection in the 21st Century [DOI]
- 3 Distribution and characterization of canine Chagas disease in Texas [DOI]
- 4 Trypanosomiasis: a veterinary perspective.
- 5 Impact of nutrition on the pathophysiology of bovine trypanosomiasis [DOI]
- 6 Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changes [DOI]
- 7 Haematology of experimental Trypanosoma brucei rhodesiense infection in vervet monkeys [DOI]
- 8 Comparative haematological study of single and mixed infections of mongrel dogs with Trypanosoma congolense and Trypanosoma brucei brucei [DOI]
- 9 Haematological, pathological and plasma biochemical changes in rabbits experimentally infected with Trypanosoma congolense [DOI]
- 10 Pathogenesis of Trypanosoma evansi infection in dogs and horses: hematological and clinical aspects [DOI]
- 11 Mechanisms Controlling Anaemia in Trypanosoma congolense Infected Mice [DOI]
- 12 The interaction of Trypanosoma congolense and Haemochus contortus infections in trypanotolerant N'Dama cattle [DOI]
- 13 The pathophysiology of ovine trypanosomosis: haemotological and blood biochemical changes [DOI]
- 14 Parasitological, Hematologic, and Immunologic Responses in Acute and Chronic Infections of Dogs with Ancylostoma ceylanicum: A Model of Human Hookworm Infection [DOI]
- 15 Pathogenesis of Trypanosoma brucei infection in deer mice (Peromyscus maniculatus): Hematologic, erythrocyte biochemical, and iron metabolic aspects [DOI]
- 16 The Association Among Blood Transfusions, White Blood Cell Count, and the Frequency of Post–Cardiothoracic Surgery Atrial Fibrillation: A Nested Cohort Study From the Atrial Fibrillation Suppression Trials I, II, and III [DOI]
- 17 The pathogenesis of anaemia in goats experimentally infected with Trypanosoma congolense or Trypanosoma brucei: Use of the myeloid:erythroid ratio [DOI]
- 18 Trypanosomiasis in Dog; A Case Report
- 19 Haemato biochemical changes in a case of canine trypanosomiasis.
- 20 Clinical signs and pathological changes in dogs with single and conjunct experimental infections of Trypanosoma brucei brucei and Ancylostoma caninum
- 21 Anaemia in trypanosomiasis : mechanisms of erythrocyte destruction in mice infected with "Trypanosoma congolense" or "T. brucei" [DOI]
- 22 Hematology of African trypanosomiasis
- 23 Enteric Nematodes of Humans
- 24 Spectrophotometry of haemoglobin: the standard haemiglobin cyanide method and after.
- 25 The effect of trypanocidal drug treatment on the haematological changes in Trypanosoma brucei brucei infected splenectomised dogs [DOI]
- 26 Constraints in the control of African trypanosomiasis the prevailing factors in Kurmin Kaduna, Northern, Nigeria (review article).
- 27 Anaemia in dogs
- 28 The effect of splenectomy on anaemia in Trypanosoma brucei infection of mice [DOI]
Cited by 0
No indexed citations yet.
Related research
- Prevalence of Canine Parvovirus in Jos North and South Local Government Areas of Plateau State — shares topic coverage
- Clinical and Physiological Characterization of Canine Distemper Virus Infection in Dogs from the Junagadh Region of Gujarat, India — shares topic coverage
- Non-Steroidal Anti-Inflammatory Drugs as Chemopreventive Agents: Evidence from Cancer Treatment in Domestic Animals — shares topic coverage
- Management of Eastern Brown and Tiger Snake Envenomation in Domestic Animals in South Australia — shares topic coverage
- Review of Incidence and Risk Factors for Spinal Fauctures in Canines — shares topic coverage
Article metrics
Real usage data collected on this platform.
44
Page views
0
PDF downloads
13
Outbound clicks
0
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.