Hepatitis B Virus Prevalence and Genotype Distribution in Human Immunodeficiency Virus Infected Patients from Brazzaville, Republic of the Congo
Brunel M. Angounda, Fabien R. Niama, Anicet L.M. Boumba, Felix Koukouikila Koussounda, Serge O. Mokono, Gabriel Ahombo
Journal of Advances in Microbiology · pp. 18–26 · Published 25 Nov 2024
10.9734/jamb/2024/v24i12869Abstract
Hepatitis B virus infection is a major global health problem, particularly in HIV-infected patients and increases the risk of liver damage. The purpose of this study was to assess the HBV prevalence and genotypes among HIV-infected patients in Brazzaville, Republic of the Congo. This cross-sectional study was conducted among HIV-positive patients attending an outpatient treatment center for HIV/AIDS in Brazzaville, from June 2018 to February 2020. Blood samples were screened for HBsAg by ELISA and HBV genotypes were determined by phylogenetic inference. Data analysis was done using SPSS V.21.0 and P value less than 0.05 was considered as statistically significant. A total of 275 patients HIV-infected were included. The prevalence of HIV-HBV coinfection was 6.9% (95%CI:4.21-10.58). The majority of the co-infected with HBV were mainly male patients (7.7%). HIV-positive individuals aged 28-38 (8.4%) were mostly affected. None of the risk’s factors tested was significantly associated with HBV in HIV-infected patients. Phylogenetic analysis revealed that 9/15 (60%) belonged to genotype E while 6/15 (40%) belonged to genotype A including subgenotypes A3 and A5. In conclusion, these data underline the importance of HBV genotype identification as an integrated measure of HIV routine care to improve the treatment of HIV/HBV co-infected patients.
References (25)
- 1 Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010 [DOI]
- 2 Global epidemiology of hepatitis B virus infection: New estimates of age-specific HBsAg seroprevalence and endemicity [DOI]
- 3 Hepatitis B: The virus and disease # [DOI]
- 4 Epidemiology of viral hepatitis and HIV co-infection [DOI]
- 5 Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 [DOI]
- 6 A new genotype of hepatitis B virus: complete genome and phylogenetic relatedness [DOI]
- 7 Epidemiology of hepatitis B virus in Africa, its genotypes and clinical associations of genotypes [DOI]
- 8 Viral Hepatitis in HIV Infection [DOI]
- 9 HIV–HBV Coinfection — A Global Challenge [DOI]
- 10 Hepatitis B virus coinfection in human immunodeficiency virus-infected patients: A review [DOI]
- 11 Influence of viral hepatitis on HIV infection [DOI]
- 12 Ketamine Causes Mitochondrial Dysfunction in Human Induced Pluripotent Stem Cell-Derived Neurons [DOI]
- 13 Hepatitis B infection among HIV infected individuals in Gabon: Occult hepatitis B enhances HBV DNA prevalence [DOI]
- 14 Serologic and genotypic characterization of hepatitis B virus in HIV-1 infected patients from South West and Littoral Regions of Cameroon [DOI]
- 15 First detection of enterovirus 71 from an acute flaccid paralysis case with residual paralysis in Iran [DOI]
- 16 Prevalence, risk factors and genotypes of hepatitis B infection among HIV-infected patients in the State of MS, Central Brazil [DOI]
- 17 Are we ready for a global pandemic of Ebola virus? [DOI]
- 18 Molecular analysis of hepatitis B virus genomes isolated from black African patients with fulminant hepatitis B [DOI]
- 19 Do MZ twins have discordant experiences of friendship? A qualitative hypothesis-generating MZ twin differences study [DOI]
- 20 Hepatitis B virus prevalence, risk factors and genotype distribution in HIV infected patients from West Java, Indonesia [DOI]
- 21 Molecular characterization of hepatitis B virus among chronic hepatitis B patients from Pointe Noire, Republic of Congo [DOI]
- 22 Hepatitis B Virus Genotypes: Clinical Relevance and Therapeutic Implications [DOI]
- 23 Prevalent Hepatitis B Virus Genotypes Circulating among HIV Co-Infected Patients in an Urban City, South-South Nigeria
- 24 Prevalence and Associated Risk Factors of Hepatitis B Virus Infections Among HIV-1 Infected Patients Attending the Comprehensive Care Clinic in Malindi Sub-County Hospital in Kenya
- 25 Hepatitis B and Hepatitis C among Human Immunodeficiency Virus Infected Patients at a District Hospital in Mwanza, Tanzania [DOI]
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