Identification of Bioactive Phytochemicals in Grewia hirsuta Vahl Leaf Extract Using GC-MS Analysis

Abstract

Grewia hirsuta, popularly known as nagbala, is extensively utilized in traditional medicine due to its remarkable pharmacological properties stemming from its diverse array of phytochemicals. In this research, Gas Chromatography-Mass Spectrometry (GC-MS) analysis was utilized to phytochemical compounds found in the methanolic extract of Grewia hirsuta vahl. GC-MS analysis shows that major bioactive compounds included 20 bioactive compounds with varying molecular structures and functional groups including silanediol. Notable pharmacologically active compounds identified were amphetamine, fluoxetine N-acetyl, nordazepam TMS derivative, and tenamfetamine. The analysis also revealed antioxidants like catechol and hydroquinone, alongside thymol Silanediol, Nortrimipramine, Butyrolactone, Catechol, m-Guaiacol, Methylphosphonic acid, Vanillin, Bupropion, Demecolcine, Lupeol, and Tetrasiloxane (decamethyl). The comprehensive understanding of the phytochemical composition of Grewia hirsuta leaf extract obtained through GCMS analysis offers valuable information for further exploration of its medicinal properties and development of novel therapeutic agents.