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Research Article Open access CC BY 4.0

Incidental Low-Grade Biliary Intraepithelial Neoplasia Following Laparoscopic Cholecystectomy: A Case Report

Anant Pore, Naresh Wamanrao Paliwal, Imran Ahmed Khan, Ravi Shyamsundar Bang, Shaikhali M Barodawala

Asian Journal of Case Reports in Surgery · pp. 202–206 · Published 28 Mar 2026

10.9734/ajcrs/2026/v9i1763

Abstract

Biliary intraepithelial neoplasia (BilIN) is a noninvasive precursor lesion that has the potential to progress to cholangiocarcinoma. A 70-year-old hypertensive female presented with complaints of recurrent abdominal pain associated with flatulence. Abdominal ultrasonography revealed cholelithiasis with no evidence of biliary dilatation or mass lesion. Histopathological examination of the cholecystectomy specimen revealed features consistent with low-grade BilIN. Routine histopathological examination is recommended for cholecystectomy patients to catch precancerous lesions in early stages for better patient management with improved outcomes.

Biliary intraepithelial neoplasia cholangiocarcinoma laparoscopic cholecystectomy precancerous conditions

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