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Research Article Open access CC BY 4.0

Lipid Profile and Prevalence of Dyslipidemia in Pre- and Postmenopausal Women in Yaounde, Cameroon

Nkeunen Gerard, Tsafack Takadong Julie Judith, Simo Gustave, Betrand Ayuk Tambe, Ayangma Celestin Roger, Tume Christopher Bonglavnyuy

International Journal of Biochemistry Research & Review · pp. 1–11 · Published 10 May 2019

10.9734/ijbcrr/2019/v25i430081

Abstract

Aims: Lipids serve several important physiologic functions like energy homeostasis or biosynthesis of hormone within the human body. The deterioration of lipid metabolism which is favoured by menopause is the source of cardiovascular diseases. This study aimed to determine the plasma lipid profile and dyslipidemia prevalence of some Cameroonian women. Study Design: This was a cross-sectional study. Place and Duration of Study: The enrollment took place at the Yaounde Military Hospital from November 2016 to July 2017. Methodology: To achieve this goal, two sets of 105 postmenopausal and 127 premenopausal participants were enrolled in this study. 5ml of blood were collected on EDTA coated tubes from each participant. Enzymatic methods were used to evaluate total cholesterol, HDL cholesterol and triglyceride, while LDL cholesterol was determined using the Friedewald equation. These biological parameters were used to determine dyslipidemia. Thereafter, they were compared within age and year since menopause subgroups. Results: There was no significant difference in the mean values of total cholesterol, HDL-C, LDL-C as well as triglyceride between premenopausal and postmenopausal women. The mean HDL-C concentration was stable in the age subgroups while the mean total cholesterol and LDL-C were slightly increasing as postmenopausal participants got older. LDL-C level was significantly higher in women who had been in menopause for more than 15 years. The overall dyslipidemia prevalence was 53%. Dyslipidemia was significantly higher in the subgroup of women who had freshly entered menopause. Conclusion: Even though there was no change in the mean concentration of the plasma lipid parameters, of pre- and postmenopausal participants there was a general need to improve their lifestyle in order to reduce dyslipidemia prevalence.

Lipid profile dyslipidemia premenopausal postmenopausal total cholesterol LDL cholesterol HDL cholesterol triglyceride

References (19)

  1. 1 Enzymatic Determination of Total Serum Cholesterol [DOI]
  2. 2 The Emergence of the Metabolic Syndrome with Menopause [DOI]
  3. 3 HDL Cholesterol and Protective Factors in Atherosclerosis [DOI]
  4. 4 Dyslipidemia Prevalence, Treatment, and Control in the Multi-Ethnic Study of Atherosclerosis (MESA) [DOI]
  5. 5 Cardiovascular disease risk reduction by raising HDL cholesterol – current therapies and future opportunities [DOI]
  6. 6 Metabolic Implications of Menopause [DOI]
  7. 7 Relationships of age, menopause and central obesity on cardiovascular disease risk factors in Chinese women [DOI]
  8. 8 Influence of menopause on serum lipids and lipoproteins [DOI]
  9. 9 Effects of Menopause on Trends of Serum Cholesterol, Blood Pressure, and Body Mass Index [DOI]
  10. 10 Longitudinal Study of Risk Factors for Coronary Heart Disease Across the Menopausal Transition [DOI]
  11. 11 Cholesterol metabolism and aging [DOI]
  12. 12 Coronary heart disease risk factors and menopause: a study in 1684 French women [DOI]
  13. 13 Hypertension, Menopause, and Coronary Artery Disease Risk in the Women’s Ischemia Syndrome Evaluation (WISE) Study [DOI]
  14. 14 Menopause, but not age, is an independent risk factor for fasting plasma glucose levels in nondiabetic women [DOI]
  15. 15 Blood lipid profile and prevalence of dyslipidemia in Chinese adults.
  16. 16 Multiple coronary heart disease risk factors are associated with menopause and influenced by substitutive hormonal therapy in a cohort of French women [DOI]
  17. 17 Postmenopausal Women Have Higher HDL and Decreased Incidence of Low HDL than Premenopausal Women with Metabolic Syndrome [DOI]
  18. 18 Lipid profile frequency and the prevalence of dyslipidaemia from biochemical tests at Saint Louis University Hospital in Senegal [DOI]
  19. 19 A STUDY ON BODY COMPOSITION AND LIPID PROFILE IN POSTMENOPAUSAL WOMEN [DOI]

Cited by 5

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Yonatan Kindie, Getnet Fetene, Abebaw Worede · BMC Endocrine Disorders · 2025

Prevalence of dyslipidemia and associated factors among post-menopausal women: a community-based comparative cross-sectional study in Debre Markos city, Northwest, Ethiopia, 2024

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