Nanomedicine in Treatment of Typhoid Fever: A Review
Swati Pund, Nitin Kharat, Shaikh Sohel Shaikh Khalil, Shoebuddin Zaheeroddin Shaikh, Chetan Pulate, Harshal Tare
Journal of Pharmaceutical Research International · pp. 16–28 · Published 15 Mar 2022
10.9734/jpri/2022/v34i24A35931Abstract
For effective management of typhoid, diagnosis of the disease must be done with speed and accuracy. Laboratory diagnosis of typhoid fever requires isolation and identification of Salmonella enterica serotype Typhi. In many areas where the disease is endemic, laboratory capability is limited. Recent advances in molecular immunology have led to the identification of sensitive and specific markers. Currently, alternative methods for biological molecular analysis are enzyme immunoassay, surface plasmon resonance and electrochemical immunoassay. With the development of nanotechnology, various nanoparticles and nano-quantum dots have been used as labels to enhance the sensitivity of the electrochemical immunoassay technique.
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