Phenolic Content and Enzyme Inhibition Activities Barbarea auriculata var. paludosa, B. integrifolia and B. plantaginea (Brassicaceae)'s
Merve Badem, Sıla Ozlem Sener, Nuriye Korkmaz, Seyda Kanbolat, Sermet Yildirmiş, Ufuk Ozgen, Rezzan Aliyazicioglu, Ali Kandemir
Journal of Pharmaceutical Research International · pp. 86–93 · Published 23 Jun 2020
10.9734/jpri/2020/v32i930486Abstract
Barbarea genus has been presented about 12 species, 9 taxon are endemic, in Turkey. In this sudy, enzyme inhibition was carried out on methanolic extract, chloroform extract, ethyl acetate extract, and the remaining aqueous phases from the aerial parts of B. auriculata var paludosa, B. integrifolia, and B. plantaginea species and HPLC studies were carried on their methanolic extract in the present study for the first time. Phenolic compounds were determined using reverse phase-high performance liquid chromatography (RP-HPLC). p-OH benzoic acid, vanilic acid, syringaldehyde, coumaric acid, synapic acid and benzoic acid were detected as major phenolic compounds in the species. Assay of enzyme inhibition activities were done using spectrophotometric methods. Results of these studies reveal that the extracts from these species have moderate tyrosinase, AChE and BuChE inhibitory activity. In the biological activity studies, it was observed that B. integrifolia was the highest activity.
References (12)
- 1 Flora of Turkey and the East Aegean Islands [DOI]
- 2 The chemical diversity and distribution of glucosinolates and isothiocyanates among plants [DOI]
- 3 Antioxidants in fruits and vegetables - the millennium's health [DOI]
- 4 Dopamine- or L-DOPA-induced neurotoxicity: The role of dopamine quinone formation and tyrosinase in a model of Parkinson’s disease [DOI]
- 5 Chemical analysis, antioxidant, antiinflammatory and anticholinesterase activities of Origanum ehrenbergii Boiss and Origanum syriacum L. essential oils [DOI]
- 6 Ginkgo extract or cholinesterase inhibitors in patients with dementia: What clinical trials and guidelines fail to consider [DOI]
- 7 Ethnobotancal Studies in the Villages of the District of Ilica (Province Erzurum), Turkey [DOI]
- 8 Xanthones from Gentianella amarella ssp. acuta with Acetylcholinesterase and Monoamine Oxidase Inhibitory Activities [DOI]
- 9 Cholinesterase inhibitory activity and chemical constituents of Stenochlaena palustris fronds at two different stages of maturity [DOI]
- 10 Investigation of antioxidant, cytotoxic, tyrosinase inhibitory activities, and phenolic profiles of green, white, and black teas [DOI]
- 11 Hypopigmentary Skin Disorders [DOI]
- 12 Determination of Phenolic Contents by HPLC, and Antioxidant, Antimicrobial, Antityrosinase, and Anticholinesterase Activities of Psephellus huber-morathii [DOI]
Cited by 7
Merve Badem, Sıla Ozlem Sener, Seyda Kanbolat · Zeitschrift für Naturforschung C · 2021
Osman Şahin, Şeyda Kanbolat, Nevin Ulaş Çolak · Chemistry & Biodiversity · 2024
Ana Alimpić-Aradski, Mariana Oalđe-Pavlović, Smiljana Janković · Lekovite Sirovine · 2021
Showing 3 of 7 known citations — external sources report more than can currently be individually listed.
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