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Research Article Open access CC BY 3.0

Prevalence of Hepatitis B Virus Infection among Egyptian Pregnant Women - A Single Center Study

Mortada EL-Shabrawi, Mohamed Farouk Mohamed, Mona Salah El Din Hamdi, Mohamed Ehab, Shaimaa Shaaban Khamiss, Hanaa El-Karaksy

International Journal of TROPICAL DISEASE & Health · pp. 157–168 · Published 2 Apr 2013

10.9734/IJTDH/2013/3276

Abstract

Background: Hepatitis B virus (HBV) infection still has a relatively high incidence and prevalence worldwide. In the post-vaccination era in developing countries, perinatal vertical transmission remains the most common mode of transmission. Prevention of mother-to-child transmission requires screening for HBV surface antigen (HBsAg) in pregnant women to identify which newborns that must be immunized. Aim: This study aimed to evaluate the prevalence of HBV infection among pregnant mothers who were attending outpatient clinic of the Obstetric Department, and Social and Preventive Medicine Center at Cairo University Hospital Campus, for routine antenatal care. Methods: A cross sectional study included 2,000 pregnant women. A rapid screening test for HBV “One Step HBsAg Rapid Test” was done for all women and all HBsAg-positive cases were confirmed by ELISA for HBsAg. A structured questionnaire for risk factors for HBV acquisition was filled for every pregnant mother positive for HBsAg and a control group of HBsAg negative mothers. Results: Out of 2,000 pregnant women, 35 (1.75%) were positive by the rapid test, out of whom 32/35 cases (91.43) were confirmed to be positive by the confirmatory test representing 1.6% of the study population. Family history of HBV, previous intravenous (IV) injections, medical clinic attendance, hospital admission, and surgeries were the risk factors for acquiring HBV infection (P-value=0.001, 0.003, 0.002, 0.000, and 0.011, respectively). Conclusion: HBV infection is prevalent among pregnant mothers attending our outpatient services. Therefore we recommend screening for HBV in all Egyptian pregnant mothers to prevent neonatal infection by immunoprophylaxis.

Prevalence epidemiology Egypt hepatitis B perinatal infection pregnancy

References (32)

  1. 1 A comprehensive immunization strategy to eliminate transmission of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP) Part II: immunization of adults.
  2. 2 PREVENTION OF PERINATALLY TRANSMITTED HEPATITIS B VIRUS INFECTIONS WITH HEPATITIS B IMMUNE GLOBULIN AND HEPATITIS B VACCINE [DOI]
  3. 3 Epidemiology of hepatitis B in Europe and worldwide [DOI]
  4. 4 HORIZONTAL TRANSMISSION OF HEPATITIS B VIRUS [DOI]
  5. 5 Introduction to Chronic Hepatitis B Infection [DOI]
  6. 6 Prevalence, correlates and pattern of hepatitis B surface antigen in a low resource setting [DOI]
  7. 7 Hepatitis B virus and hepatitis C virus in pregnant Sudanese women [DOI]
  8. 8 HEPATITIS B IN IRAN
  9. 9 Hepatitis B infection is highly endemic in Uganda: findings from a national serosurvey.
  10. 10 Surveying infections among pregnant women in the Niger Delta, Nigeria [DOI]
  11. 11 Maternal and neonatal seroprevalence of Hepatitis B surface antigen (HBsAg) in Tripoli, Libya [DOI]
  12. 12 Prevalence of hepatitis B and C in Egypt and Africa.
  13. 13 Public Health Management of Perinatal Hepatitis B Virus [DOI]
  14. 14 Prevalence of Hepatitis B Surface Antigen and Risk Factors of HBV Infection in a Sample of Healthy Mothers and Their Infants in Sana'a, Yemen [DOI]
  15. 15 THE SEROPREVALENCE OF HEPATITIS B SURFACE ANTIGEN AND HUMAN IMMUNODEFICIENCY VIRUS AMONG PREGNANT WOMEN IN ANAMBRA STATE, NIGERIA
  16. 16 Hepatitis B surface antigen in saliva, impetiginous lesions, and the environment in two remote Alaskan villages [DOI]
  17. 17 Seroprevalence of hepatitis B in pregnant women in Mexico [DOI]
  18. 18 Prevalence of hepatitis B surface antigen in vaccinated children and controls in rural Nigeria [DOI]
  19. 19 Risk of Perinatal Transmission of Hepatitis B Virus in Jordan [DOI]
  20. 20 Comparison of frequency of hepatitis B and hepatitis C in pregnant women in urban and rural area of district Swat.
  21. 21 Hépatite virale B chez les femmes enceintes tunisiennes : facteurs de risque et intérêt de l’étude de la réplication virale en cas d’antigène HBe négatif [DOI]
  22. 22 Serosurvey of hepatitis B surface antigen in pregnant Saudi women.
  23. 23 Prevalence of HBsAg and high-risk behaviors in pregnant women rerring to Urban Health Centers in Isfahan province.
  24. 24 Hepatitis B virus seroprevalence among parturients in Accra, Ghana [DOI]
  25. 25 Frequency of anti-HCV, HBsAg and related risk factors in pregnant women at Nishtar Hospital, Multan.
  26. 26 Seroprevalences of Hepatitus B surface antigenaemia in children in a tertiary health institution in the Niger Delta of Nigeria [DOI]
  27. 27 Perinatal transmission of Hepatitis B [DOI]
  28. 28 Patterns of hepatitis B infection in Egyptian children in the era of obligatory hepatitis B vaccination [DOI]
  29. 29 Weighted analysis of prevalence and risk factors of hepatitis B infection among antenatal mothers in Ipoh.
  30. 30 Perinatal transmission of hepatitis B. [DOI]
  31. 31 Hepatitis B Virus Infection among Pregnant Women in Northeastern Romania [DOI]
  32. 32 Hepatitis B en gestantes y niños [DOI]

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