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Research Article Open access CC BY 4.0

Prevalence of Malaria and Helicobacter Pylori Coinfection and Associated Sociodemographic Factors among Blood Donors in Douala General Hospital

Watching Djakissam, Thelma Epole Agberndifor, Ndouwe Tissebe Menga Honore, Ebude Roda Nzegge, Zeuko’o Menkem Elisabeth, Yimtchi Ngassa Christian Lavoisier, Abange William Baiye, Emmanuel Rode Mengue

International Journal of TROPICAL DISEASE & Health · pp. 1–12 · Published 5 Apr 2024

10.9734/ijtdh/2024/v45i61534

Abstract

Background: The malaria parasite Plasmodium is intra-erythrocyte hence can be transmitted by transfusion of any blood component containing infected red blood cells. Helicobacter pylori infection affects more than half of the human population worldwide. Infection remains asymptomatic in most individuals, although some individuals develop acute gastritis, peptic or duodenal ulcers, gastric cancer, and mucosa associated tissue lymphoma. H. pylori infection have been implicated in some haematological manifestations such as anaemia and micronutrient deficiency. Objective: This research was designed to determine the prevalence of malaria parasitaemia and H. pylori coinfection in association with sociodemographic characteristics among donors in Douala General Hospital. Methodology: The study was a hospital-based study carried out from January to May 2022. The study population comprised of 106 donors who came to the hospital laboratory for blood donation. A structured questionnaire was used to get demographic and clinical data. Two ml of blood was collected from individuals to prepare a thick and thin blood film for malaria parasite determination and to centrifuge at 3000 rpm for 5 minutes to obtain plasma for H. pylori test strip. Results and Discussion: The overall prevalence of H. pylori in the study area was 70.8%. The female donors had a prevalence of 72.0%. A greater proportion of blood group O donors had H. pylori than groups A, AB and B but this difference was not significant (P-value = 0.571). The prevalence of malaria parasites infection was 36.8%. Those of blood group A had a higher prevalence rate of 42.3% (11/26). Out of the 106 donors, 23 (21.7%) had malaria and H. pylori coinfection. 68 (64.2%) donors had a mono-infection that is either having malaria mono-infection or H. pylori mono-infection and 15 (14.2%) had no infection. Malaria and H. pylori coinfection was higher in female donors than males (OR = 1.059, 95% Cl 0.359 -3.119, P =0.917), in donors aged below 25 years old (OR = 0.338, 95% Cl 0.075 - 1.535, P =0.160), replacement donors (OR = 1.350, 95% Cl 0.460 – 3.964, P =0.585); blood donors of blood group AB (OR = 0.654, 95% Cl 0.181 – 2.366, P =0.517) and Rhesus negative donors (OR = 1.500, 95% Cl 0.130 – 17.36, P =0.746). Conclusion: The prevalence of H. pylori infection and Malaria among blood donors in Douala General Hospital were high and coinfection was higher in females than males. Both malaria parasites and H. pylori infections have been implicated in blood parameters such as anaemia and micronutrient deficiency. It is therefore recommended that routine screening for malaria parasites and H. pylori be done in   blood banks before transfusion for a high blood quality.

Malaria parasites helicobacter pylori blood donors Cameroon

References (23)

  1. 1 THE JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
  2. 2 Malaria and blood transfusion [DOI]
  3. 3 Prevalence of Helicobacter pylori and Its Associated Factors among Healthy Asymptomatic Residents in the United Arab Emirates [DOI]
  4. 4 Potential risk factors and prevalence of Helicobacter pylori infection among adult patients with dyspepsia symptoms in Cameroon [DOI]
  5. 5 Transfusion-Transmitted Malaria in Ghana [DOI]
  6. 6 Seroprevalence of Helicobacter pylori infection in an asymptomatic Turkish population [DOI]
  7. 7 Potential risk of induced malaria by blood transfusion in South-eastern Nigeria [DOI]
  8. 8 The prevalence of malaria parasitaemia in blood donors in a Nigerian teaching hospital.
  9. 9 Seroprevalence of Helicobacter pylori infection and its related risk factors in symptomatic patients in southern Ethiopia [DOI]
  10. 10 Prevalence of Helicobacter pylori among Patients with Gastrointestinal Tract (GIT) Symptoms: A Retrospective Study at Selected Africa Air Rescue (AAR) Clinics in Kampala, Uganda, from 2015 to 2019 [DOI]
  11. 11 Helicobacter pylori and its hematological effect [DOI]
  12. 12 Asymptomatic Malaria among Blood Donors in Benin City Nigeria.
  13. 13 Transfusion-transmitted malaria: donor prevalence of parasitaemia and a survey of healthcare workers knowledge and practices in a district hospital in Ghana [DOI]
  14. 14 Asymptomatic Malaria and its Challenges in the Malaria Elimination Program in Iran: a Systematic Review.
  15. 15 Sero-prevalence of Helicobacter pylori infection among asymptomatic healthy Omani blood donors [DOI]
  16. 16 Prevalence of Helicobacter pylori infection among asymptomatic healthy blood donors in Northern Peninsular Malaysia [DOI]
  17. 17 An update of malaria infection and anaemia in adults in Buea, Cameroon [DOI]
  18. 18 High Risk of Transfusion-Transmitted Malaria (TTM) from Student Blood Donors Living in the Town of Douala, Cameroon [DOI]
  19. 19 Residual risk of transfusion-transmitted malaria infection in a malaria endemic sub-Saharan African setting [DOI]
  20. 20 The prevalence of malaria parasitaemia and predisposition of ABO blood groups to Plasmodium falciparum malaria among blood donors at a Ghanaian hospital.
  21. 21 Prevalence of malaria parasite among blood donors in Lagos University Teaching Hospital, Lagos Nigeria.
  22. 22 The risk of transfusion transmitted malaria and the need for malaria screening of blood donors in Abuja, Nigeria [DOI]
  23. 23 The Prevalence of Helicobacter pylori Infections among Blood Donors in Blood Bank of Zawia Teaching Hospital and the Assessment of Some Related Factors [DOI]

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