Prevalence, Risk Factors and Predictors of Mortality Outcome in Neonatal Sepsis in KSA: Systematic Review

Abstract

The systemic reaction to infection in newborn infants during the first 28 days of life has been referred to as neonatal sepsis. Global health issues include neonatal sepsis. Furthermore, newborn sepsis contributes significantly to morbidity and mortality in underdeveloped nations. This study examined the prevalence, risk factors, aetiology, death rate, and outcomes of neonatal sepsis in newborns in the Kingdom of Saudi Arabia. On the same subject, a thorough search of the literature was done using online databases like PubMed, Embase, and Google Scholar. After removing 45 duplicates, a total of 119 articles were found in the initial systematic search. 25 studies were removed after title and abstract screening on 74 study papers. Only 16 papers out of 49 total items that underwent full-text evaluation met the requirements for inclusion in this meta-analysis. We took research that were released between January 1997 and December 2021. We only looked for English-language studies during our search. Neonatal sepsis is a major public health problem due to its rising occurrence; therefore, it is crucial to look at its epidemiology, risk factors, and clinical characteristics. Since gluten is now well recognised as a precipitating factor, current research is helping to better understand the other aspects of this syndrome.