Seroprevalence of Cytomegalovirus (CMV) Amongst Voluntary Blood Donors in University of Benin Teaching Hospital (UBTH), Edo State, Nigeria
C. K. Ojide, E. A. Ophori, N. O. Eghafona, C. Omoti
Journal of Advances in Medicine and Medical Research · pp. 15–20 · Published 12 Nov 2011
10.9734/BJMMR/2012/621Abstract
Aim: To investigate the seroprevalence of cytomegalovirus (CMV) among voluntary blood donors in University of Benin Teaching Hospital (UBTH), Nigeria with the purpose of determining whether routine CMV screening for donors is justified or not. Place and Duration of Study: Department of Haematology and Department of Medical Microbiology, University of Benin Teaching Hospital (UBTH), Benin city, Nigeria, between May and September, 2010. Methodology: Sera from randomly selected one hundred and ninety-two (192) voluntary blood donors, consisting of 176 males and 16 females that visited the hospital from May to September 2010 were evaluated for CMV-IgG and IgM antibodies using an enzyme-linked immunosorbent assay (ELISA) based kit. Results: Seroprevalence for CMV-IgG and IgM were 95.8% and 3.1% respectively. All female donors (n=16) were positive for IgG. A total of 114 out of 192 (59.4%) donors were within the age bracket of 30-39 years. A prevalence of 100% for CMV IgG antibody was observed in age group ≥50 years, Conclusion: Routine screening of donors for CMV-IgG antibody would amount to waste of resources given the high prevalence of 95.8%. Periodic screening to identify the small percentage of seronegative blood donors (4.2%) who are needed for the ever increasing number of immunosuppressed recipients is recommended.
References (18)
- 1 Complement-fixing antibodies against cytomegalovirus in different parts of the world.
- 2 Summary of the II International Symposium on Cytomegalovirus [DOI]
- 3 Continuous cytomegalovirus seroconversion in a large group of healthy blood donors [DOI]
- 4 Detection of Human Cytomegalovirus DNA, RNA, and Antibody in Normal Donor Blood [DOI]
- 5 Seroprevalence of cytomegalovirus among voluntary blood donors in Delhi, India.
- 6 CYTOMEGALOVIRUS INFECTION: AN INDIAN PERSPECTIVE [DOI]
- 7 Transfusion transmission of cytomegalovirus confirmed by restriction endonuclease analysis [DOI]
- 8 Predictive value of maternal-IgG avidity for congenital human cytomegalovirus infection [DOI]
- 9 Seroprevalence of cytomegalovirus among some voluntary blood donors at the 37 military Hospital, Accra, Ghana [DOI]
- 10 Seroprevalence of Cytomegalovirus among Voluntary Blood Donors [DOI]
- 11 Cytomegalovirus Studies on Blood Donors in North‐East Scotland and a Review of UK Data [DOI]
- 12 Cytomegalovirus antibodies among healthy blood donors at Lagos University Teaching Hospital. [DOI]
- 13 The Seroprevalence of Cytomegalovirus Antibodies among Prospective Blood Donors in Jos [DOI]
- 14 Detection of cytomegalovirus in blood donors by PCR using the digene SHARP signal system assay: effects of sample preparation and detection methodology [DOI]
- 15 Transfusion-Associated Infections with Cytomegalovirus and Other Human Herpesviruses [DOI]
- 16 Sécurité transfusionnelle: Risques émergents ou hypothétiques [DOI]
- 17 Relation of Titers of Antibodies to CMV in Blood Donors to the Transmission of Cytomegalovirus Infection [DOI]
- 18 DETECTION OF HUMAN CYTOMEGALOVIRUS [DOI]
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