Skip to content
Research Article Open access CC BY 4.0

Sexual Invigorating Potentials of a Combined Extract of Sabicea calycina and Carpolobia lutea on Male Wistar Rats in Crude Oil Challenged Environment

Kpomah E. D., Osioma E., Agoro E. S.

International Journal of Biochemistry Research & Review · pp. 39–54 · Published 24 Jan 2024

10.9734/ijbcrr/2024/v33i1851

Abstract

The effect of 50, 100 and 200 mg/kg of combined ethanol extract of S. calycina and C. lutea were investigated on mating behavioural parameters and sex/reproductive hormone boosting potentials in both non-bonny light crude oil (NBLCO) and bonny light crude oil (BLCO) environmentally challenged rats. Forty sexually experienced rats weighing 120-135g were arbitrarily allocated into two groups of twenty rats as NBLCO and BLCO respectively, each group were further subdivided into four groups of five rats and administered orally with 50 mL distilled water (control) and the extract of S. calycina and C. lutea at doses of 50, 100 and 200 mg/kg body weight. After 21 days of treatment protocols, the animals were observed for both precopulatory and copulatory activities, sex hormone was also evaluated. The copulatory activities monitored showed that mount latency, intromission latency and post ejaculatory intervals were significantly decreased by the 100 and 200 mg/kg of the extract in both the NBLCO and BLCO-challenged rats (P < 0.05). All doses significantly increased (P < 0.05) the mount frequency, intromission frequency, and ejaculatory frequency in the NBLCO groups while only the 100 and 200 mg/kg body weight was able. Copulatory efficiency was significantly increased (P < 0.05) by all doses in a dose-related manner in the NBLCO groups while only the 200 mg/kg dose level was able to significantly increase (P < 0.05) the copulatory efficiency in the BLCO groups. The hormonal assay showed that all doses produced a significant increase (P < 0.05) in testosterone, luteinizing hormone, follicle-stimulating hormone, and progesterone, with a concomitantly significant decrease (P < 0.05) in prolactin in the NBLCO groups, however, only the 100 and 200 mg/kg was able to able to achieve significant change (P < 0.05) in these hormonal levels in the BLCO groups. Findings from this study showed that the extract has aphrodisiac potentials and also the ability to restore hyposexual activity in rats challenged with crude oil. 

Aphrodisiac C. lutea S. calycina copulatory activity sex hormones

References (43)

  1. 1 Clinical Guide to Laboratory Tests. [DOI]
  2. 2 Ethnobotanical survey of Akwa Ibom State of Nigeria [DOI]
  3. 3 The human health implications of crude oil spills in the Niger delta, Nigeria: An interpretation of published studies [DOI]
  4. 4 Male sexual dysfunction: A review of literature on its pathological mechanisms, potential risk factors, and herbal drug intervention [DOI]
  5. 5 An audit of diagnosis and treatment of tuberculosis in Ethiopia [DOI]
  6. 6 Male Sexual Dysfunction and Methods used in Assessing Medicinal Plants with Aphrodisiac Potentials
  7. 7 The role of testosterone in male sexual function [DOI]
  8. 8 Male Sexual Dysfunction [DOI]
  9. 9 Recent findings on natural products with erectile-dysfunction activity [DOI]
  10. 10 A review of the herbal phosphodiesterase inhibitors; Future perspective of new drugs [DOI]
  11. 11 Energy Expenditure during Sexual Activity in Young Healthy Couples [DOI]
  12. 12 Effect of Withania somnifera root extract on the sexual behaviour of male rats.
  13. 13 Prevalence and risk factors of erectile dysfunction in Niger delta region, Nigeria [DOI]
  14. 14 Sexuality in Ageing Male: Review of Pathophysiology and Treatment Strategies for Various Male Sexual Dysfunctions [DOI]
  15. 15 Epidemiology and Treatment Barriers of Patients With Erectile Dysfunction Using an Online Prescription Platform: A Cross-Sectional Study [DOI]
  16. 16 Medications Most Commonly Associated with Erectile Dysfunction: Evaluation of the Food and Drug Administration National Pharmacovigilance Database [DOI]
  17. 17 Prevalence of sexual dysfunctions and associated risk factors in Poland [DOI]
  18. 18 The achievement of glycaemic, blood pressure and LDL cholesterol targets in patients with type 2 diabetes attending a South African tertiary hospital outpatient clinic [DOI]
  19. 19 Carpolobia lutea roots restore sexual arousal and performance in paroxetine-induced sexually impaired male rats [DOI]
  20. 20 Neglected sexual dysfunction symptoms amongst chronic patients during routine consultations in rural clinics in the North West province [DOI]
  21. 21 Copulatory efficiency and fertility in male rats exposed perinatally to flutamide [DOI]
  22. 22 Male sexual dysfunction [DOI]
  23. 23 Prescribing patterns and costs associated with erectile dysfunction drugs in England: a time trend analysis [DOI]
  24. 24 Prevalence, severity, and correlates of erectile dysfunction among male adult patients of a primary care clinic in North-West Nigeria [DOI]
  25. 25 Timing of Penile Color Flow Duplex Ultrasonography Using a Triple Drug Mixture [DOI]
  26. 26 Spermatotoxic impact of bonny light crude oil (BLCO) ingestion on adult male Swiss albino mice [DOI]
  27. 27 Sex Therapy: A Practical Guide [DOI]
  28. 28 Influence of prolonged exposure to Nigerian Bonny light crude oil on fertility indices in rats.
  29. 29 Effect of Pumpkin Extract (Telfairia occidentalis) on Routine Haematological Parameters in Acetone-Induced Oxidative Stress Albino Rats [DOI]
  30. 30 An Overview: Some Medicinal Plants as Aphrodisiac Agents [DOI]
  31. 31 Antimicrobial, antioxidant, anthelmintic and anti-inflammatory bioactivities of Sabicea calycina [DOI]
  32. 32 Impact of body composition analysis on male sexual function: A metabolic age study [DOI]
  33. 33 Comparative Phytochemical, Proximate and Some Mineral Composition of the Leaves and Stem Bark of Spondia mombin (L. anacardiaceae) [DOI]
  34. 34 Effect of Withania somnifera root extract on the sexual behaviour of male rats
  35. 35 Maternal exposure to Bonny Light Crude Oil Altered Reproductive indices in Male and Female offspring of Wistar rats.
  36. 36 Analysis of the Impact of Oil Revenue on the Nigerian Economy [DOI]
  37. 37 Alterations in chromatin DNA and protein absorbance ratio in the liver of albino rats (Rattus norvegicus) treated with bonny light crude oil
  38. 38 Erectile dysfunction among men attending surgical outpatients Department in a Tertiary Hospital in South-Western Nigeria [DOI]
  39. 39 Timing of Penile Color Flow Duplex Ultrasonography Using a Triple Drug Mixture [DOI]
  40. 40 PROLONGED INGESTION OF CRUDE OIL SPILL CONTAMINATED WATER AFFECTS MALE REPRODUCTIVE SYSTEM, HORMONES AND ACCESSORY ORGANS IN WISTAR RATS [DOI]
  41. 41 International Journal of Pharmaceutical Sciences Review and Research [DOI]
  42. 42 Medicinal plants of the world [DOI]
  43. 43 Treating Low Sexual Desire in Men [DOI]

Cited by 1

Aphrodisiac activity of ethanolic root extracts of Acacia pycnantha (Golden Wattle) in healthy male Wistar rats

Enyohwo Dennis Kpomah, Owo Gogo James, Bridget Kpomah · Journal of Research in Applied and Basic Medical Sciences · 2025

Related research

Article metrics

Real usage data collected on this platform.

49

Page views

0

PDF downloads

8

Outbound clicks

1

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.