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All published articles 234

Severity and Lethality of Cancers in Tunisia: Empirical Modeling Insights from GLOBOCAN 2020 Estimates

Nesrine Mejri, Myriam Saadi, Lilia Ghorbal, Senyefia Bosson-Amedenu, Theodore Oduro-Okyireh, Anthony Joe Turkson & Noureddine Ouerfelli · International Research Journal of Oncology · 2026

Background: Cancer incidence and mortality impose a substantial health burden in Tunisia. Understanding the relationships among key epidemiological indicators is essential for assessing cancer patterns and their public health implications. Aim: This study examined patterns in nat...

Open access Research Article 10.9734/irjo/2026/v9i2235

The Cancer Organoid Digital Twin: A Critical Review of AI-Enabled Patient-Specific Modeling of Drug Response, Resistance, and Tumor Evolution

Richard Afriyie Osei, Olaitan Ebenezer Oluwadare & Olatunde Simeon Awolola · International Research Journal of Oncology · 2026

The integration of patient-derived cancer organoids with artificial intelligence (AI) offers a potential approach for developing more individualised models of tumour behaviour and therapeutic response. Conventional precision oncology relies heavily on static molecular measurement...

Open access Research Article 10.9734/irjo/2026/v9i2234

Enablers and Barriers to Prostate Cancer Screening in Africa: A Critical Narrative Review of Individual, Sociocultural and Health-System Determinants

Akhilele, Ernest Eromosele, Tama, Sudhir Caleb, Nkene, Istifanus Haruna, Akyala, Isaac Adamu & Ambi, Ibrahim Mamman · International Research Journal of Oncology · 2026

Prostate cancer is a major and increasing cause of cancer morbidity and mortality among African men, yet the value of early detection depends on more than whether a prostate-specific antigen test is available. Screening decisions are shaped by knowledge, perceived susceptibility,...

Open access Research Article 10.9734/irjo/2026/v9i2233

Epigenetic Drivers of Resistance to Androgen Deprivation in Prostate Cancer: A Critical Appraisal of Mechanisms, Evidence Quality and Therapeutic Translation

Adesina Saheed Musa, Felix Olayemi Fagbomedo, Adeniyi Taofeeq Abiodun, Marcia Fernando Mariano & Isabel’s Bartolomeu Pascoal · International Research Journal of Oncology · 2026

Androgen deprivation remains the therapeutic foundation of advanced prostate cancer, yet the durability of response is limited and progression to castration-resistant disease is close to universal. Genomic explanations centred on androgen receptor amplification, point mutation an...

Open access Research Article 10.9734/irjo/2026/v9i2232

Awareness of Male Breast Cancer among Male Undergraduate Students in Abia State University, Uturu

Uka-Kalu, Ezinne Chioma, Uche, Onyinyechi Maryjane & Nwagu Chinenye Mary · International Research Journal of Oncology · 2026

Background: Male Breast Cancer (MBC) is a rare but serious malignancy often diagnosed at advanced stages due to a profound lack of awareness. In Nigeria, MBC remains understudied, particularly among young male populations in tertiary institutions. Objective: This study assessed t...

Open access Research Article 10.9734/irjo/2026/v9i2231

Human Papillomavirus Vaccination Uptake and Perceived Barriers among Women Attending Abia State University Teaching Hospital, Aba, Nigeria

Emmanuel M. Akwuruoha, David O. Akwuruoha, Vanessa A. Chigbundu & Augustine I. Airaodion · International Research Journal of Oncology · 2026

Background: Human papillomavirus (HPV) vaccination remains one of the most effective strategies for preventing cervical cancer. However, vaccine uptake among women in many low- and middle-income countries remains suboptimal due to social, economic, and health system challenges. A...

Open access Research Article 10.9734/irjo/2026/v9i2230

Recurrent Extraperitoneal Pelvic Desmoplastic Small Round Cell Tumor Treated by Total Pelvic Exenteration: A Case Report

Houmada Amina, El Hassouni Mohammed Reda, LAHNAOUI Oumayma, El Bouazizi Yassine, EL MOUATASSIM Zakaria, MAJBAR Mohammed Anass & SOUADKA Amine · International Research Journal of Oncology · 2026

Background: Desmoplastic small round cell tumour (DSRCT) is a rare, aggressive mesenchymal neoplasm that typically disseminates along the peritoneal and serosal surfaces of the abdominopelvic cavity in adolescent and young adult males. Isolated presentations confined to a non-ser...

Open access Research Article 10.9734/irjo/2026/v9i2229

Treatment-free Remission in Chronic Myeloid Leukaemia: A Critical Appraisal of the Evidence, Persistent Uncertainties and Research Priorities

Nilkamal Kumar & Nishant Sinha · International Research Journal of Oncology · 2026

Chronic myeloid leukaemia (CML) has been transformed by BCR::ABL1 tyrosine kinase inhibitors (TKIs), and for many patients life expectancy now approaches that of the general population. Against this background, treatment-free remission (TFR), defined as the maintenance of molecul...

Open access Research Article 10.9734/irjo/2026/v9i2228

Conjunctival CD20-Positive B-Cell Lymphoma with High-Grade Cytological Features in a Young Adult Mimicking a Benign Conjunctival Lesion: A Case Report

Lotfi Chaabani, Ines Bouallegui, Mohamed Said, Laila Ferchichi & Abdelghani Chaabani · International Research Journal of Oncology · 2026

Aims: To report an unusual case of conjunctival CD20-positive B-cell lymphoma with high-grade cytological features in a young adult that initially mimicked a benign conjunctival lesion, and to emphasise the diagnostic limitations of a restricted immunohistochemical panel. Present...

Open access Research Article 10.9734/irjo/2026/v9i2227

Effectiveness of a Structured Teaching Programme on Knowledge Regarding the Prevention of Lung Cancer among Adults Working in a Selected Industry at Coimbatore, India

Suganthakumari Francis, S. Sowmiya, S. Nisha & A. Ishwarya · International Research Journal of Oncology · 2026

Background: Industrial workers may encounter occupational and lifestyle-related risk factors for lung cancer, while their knowledge of preventive measures may be limited. Aims: This study evaluated the effectiveness of a structured teaching programme on knowledge regarding lung c...

Open access Research Article 10.9734/irjo/2026/v9i2226

COVID-19 Vaccination-Induced PET/CT False Positives in a Patient with Melanoma: A Case Report and Literature Review

Mohammed Reda El Hassouni, Yassine El Bouazizi, Amina Houmada, Oumayma Lahnaoui, Zakaria El Mouatassim & Amine Souadka · International Research Journal of Oncology · 2026

Background: COVID-19 vaccination may produce transient hypermetabolic lymphadenopathy that complicates oncological imaging and can resemble metastatic disease. Case Presentation: A 45-year-old woman with a history of superficial spreading melanoma of the left forearm underwent PE...

Open access Research Article 10.9734/irjo/2026/v9i2225

Uptake and Determinants of Cervical Cancer Screening in Rural Communities of Rivers State, Nigeria

Nduye Christie Tobin Briggs & Obeleye Tom-George · International Research Journal of Oncology · 2026

Background: Cervical cancer remains a leading cause of cancer-related death among women in sub-Saharan Africa, yet screening uptake in rural Nigeria is critically low. This study determined the uptake and determinants of cervical cancer screening among women in rural communities...

Open access Research Article 10.9734/irjo/2026/v9i2223

Risk Factors, Presenting Symptoms, Time of Diagnosis for Women with Breast Cancer in Baghdad Province

Nabaa Sadeq Idan & Abbas Al-Mizraqchi · International Research Journal of Oncology · 2026

Background: Breast cancer is a major health concern among women, and delayed recognition of warning signs may contribute to diagnosis at an advanced stage. Objective: This study described risk factors, presenting symptoms, and the time of diagnosis among women with breast cancer...

Open access Research Article 10.9734/irjo/2026/v9i2224

Explainable Adaptive Metaheuristic Optimization for Feature Selection in Breast Cancer Diagnosis: A Review of Transparent and Effective AI Approaches

Mohammed Raihanatu Hamid, Mustapha Ismail & Muhammad Kabir Ahmed · International Research Journal of Oncology · 2026

Breast cancer remains the most frequently diagnosed malignancy among women worldwide, and computer-aided diagnostic systems built on machine learning have become central to early detection efforts. A persistent obstacle to clinical adoption is the tension between predictive accur...

Open access Research Article 10.9734/irjo/2026/v9i2222

Ki-67 Expression and Its Prognostic Significance in Breast Carcinoma: A Systematic Review

Fritz A. Bucao, Eunice Fay B. Cayacap, Chanelie Bacacao Tabliga & Aisha Jae Moreno Cabilao · International Research Journal of Oncology · 2026

Background: Breast carcinoma remains the most frequently diagnosed cancer among women worldwide and a major cause of cancer-related mortality. Ki-67, a nuclear proliferation marker expressed during active phases of the cell cycle, has become an important immunohistochemical bioma...

Open access Research Article 10.9734/irjo/2026/v9i2221