Neurodegenerative diseases and cognitive decline pose significant global health challenges. The Kelch-like ECH-associated protein 1 (Keap1) – nuclear factor erythroid 2-related factor 2 (Nrf2) pathway is a master regulator of cellular defense against oxidative stress and inflamma...
Open access
Research Article10.9734/indj/2025/v22i4500
Mental health problems, including sadness and anxiety, have become important public health issues that affect more than 280 million people around the world. For treatment to work, it is important to diagnose problems early and start treatment right once. Unfortunately, standard t...
Open access
Research Article10.9734/indj/2025/v22i4499
Background: Adolescence constitutes a critical developmental stage marked by the onset of mental health difficulties, yet timely access to effective mental health care remains a significant challenge for many adolescents in the United Kingdom (UK). Artificial intelligence (AI)-en...
Open access
Research Article10.9734/indj/2025/v22i4498
Aims: This study examines changes in various defense mechanisms as individuals transition from a healthy state of mind to a depressed state, as well as the prevalence of different defense mechanisms. Study Design: Hospital- and Community-Based Cross-Sectional Study Place and Dura...
Open access
Research Article10.9734/indj/2025/v22i4497
Background: Though there are several studies on the efficacy of escitalopram in the management of depression and anxiety disorders, there is a dearth of studies among clinicians regarding their perspectives. This study assesses clinician preferences for escitalopram across vario...
Open access
Research Article10.9734/indj/2025/v22i4496
Eduardo Fernandes de Miranda, Deyvison José da Silva, Rayane Cavenage Silva, Fernanda Martins Silva, Maria Clara de Almeida Souza, Helen Castro Dantas Rodrigues, Maisa Bruna de Morais Teixeira do Nascimento, Andressa Sena Rodrigues, Carina Souza de Melo, Daniela Leão da Costa, Laís Tonello & Iransé Oliveira-Silva·International Neuropsychiatric Disease Journal·2025
Introduction: University students face challenges that impact both their physical and mental health. However, studies that integrate depressive symptoms, sleep quality, chronotype, and cardiorespiratory fitness remain scarce. Objective: This study aimed to analyze the relationshi...
Open access
Research Article10.9734/indj/2025/v22i4495
Background: The increasing rate of substance abuse and its adverse effects on physical and psychosocial health is a public health concern affecting adolescents. Psychoeducation has shown to be an effective treatment intervention in psychotherapy and patient education. This study...
Open access
Research Article10.9734/indj/2025/v22i4494
Felix Keneolisa Asogwa, Daniel Lotanna Ajaghaku, Augustine Oluchukwu Asogwa, Levi Onyebuchi Idokoja, Detu Martins Ikpechukwu & Damian Chukwunonso Mbah·International Neuropsychiatric Disease Journal·2025
Schizophrenia is a disorder characterized by a multifaceted pathogenic mechanism impacted by numerous genes. The investigation of its pathophysiology is mostly dominated by the dopamine hypothesis. Multi-target therapies represent a viable strategy for addressing polygenic disor...
Open access
Research Article10.9734/indj/2025/v22i4492
Ekbom syndrome or delusional parasitosis is a rare disorder characterized by the unshakeable and fixed belief that the skin is infested by insects or parasites. It is a monothematic delusion of hallucinatory origin, which can affect men or woman independent the old. We report the...
Open access
Research Article10.9734/indj/2025/v22i4491
Background & Aim: To express a perspective on cortical homunculus as a universal memory storehouse and control centre of an organism. The cortical homunculus, the “little human” in the brain is the internal representation of human body parts within the sensory and motor domai...
Open access
Research Article10.9734/indj/2025/v22i4490
Pharmacogenomic testing can identify these genetic variations, allowing healthcare providers to adjust drug selection and dosage accordingly. These tests typically involve a simple cheek swab or saliva sample, which is then analysed to identify specific genetic variations that af...
Open access
Research Article10.9734/indj/2025/v22i4489
Rohypnol, scientifically known as flunitrazepam, is a potent benzodiazepine medication primarily prescribed for the treatment of severe insomnia and as a pre-anesthetic medication. However, its reputation has been tarnished by its misuse as a recreational drug and its association...
Open access
Research Article10.9734/indj/2025/v22i3487
Background: Cyberbullying and cyberstalking are emerging challenges, especially among youths, owing to the growing penetration of social media and digital platforms. Despite the global awareness of their psychological consequences, specific data from Gujarat, India, remains scarc...
Open access
Research Article10.9734/indj/2025/v22i4488
Bulimia nervosa (BN) is a severe psychiatric disorder characterized by recurrent episodes of binge eating followed by compensatory behaviors, such as self-induced vomiting, misuse of laxatives, and excessive exercise. The oral and dental repercussions of BN can be profound, and d...
Open access
Research Article10.9734/indj/2025/v22i3493
Mitochondria play a fundamental role in cell bioenergetics and respiratory processes, both of which are necessary for the myriad of metabolic responses that sustain cellular vitality. Mitochondrial dysfunction in neuronal cells facilitates the generation of reactive oxygen specie...
Open access
Research Article10.9734/indj/2025/v22i3486