Climate change is an inexorable global phenomenon with far-reaching implications for mental and physical health as well as biodiversity. Extreme weather patterns, including natural disasters, account for a wide-range of reproductive, neuropsychiatric, and neurodegenerative condit...
Open access
Research Article10.9734/indj/2025/v22i3483
Aims: This study examined the impact of workplace stressors on employees’ subjective well-being and evaluated the mediating role of coping strategies and the moderating role of mindfulness within this relationship. Study Design: A cross-sectional quantitative survey design was em...
Open access
Research Article10.9734/indj/2025/v22i3484
Objective: This study explored life satisfaction, depression, and quality of life (QoL) among retired public servants in southwest Nigeria. It also examined how financial support, social support, gender, and religiosity affect well-being after retirement. Materials and Methods: T...
Open access
Research Article10.9734/indj/2025/v22i3485
Recent studies focusing on the combination of psychotherapy and transcranial direct current stimulation (tDCS) showed debatable results for an additional effect of tDCS in depression. Here, we aim at evaluating the effects of tDCS adjunct to a multimodal psychosomatic treatment....
Open access
Research Article10.9734/indj/2025/v22i3482
Chlorpromazine CPZ, a widely used antipsychotic, has been linked to neurological side effects, including tardive dyskinesia, and evidence suggests a potential for long-term neurotoxic effects. This review synthesizes findings from in vitro and in vivo studies investigating the im...
Open access
Research Article10.9734/indj/2025/v22i3481
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss, significantly impacting millions worldwide. The accumulation of amyloid-β (Aβ) plaques in the brain is a central feature of AD pathology, making it a key targe...
Open access
Research Article10.9734/indj/2025/v22i3480
Alzheimer's disease (AD), a progressive and unrelenting memory loss, gradually weakens cognitive and independent functioning. There is currently no cure despite decades of research, and existing medicines simply alleviate symptoms. A complex interaction between hereditary variabl...
Open access
Research Article10.9734/indj/2025/v22i3479
Eru, E.M, Theresa I. Ekpenyong, Cyril A. Agbor, Christie E. Fischer, Michael E. Oku, Samson O. Paulinus, Etim D. Isaiah, Kelechi C. Uruakpa, Williams A. Nnenna, Nsikak M. Umoh, Eric A. Agaba & Anozeng O. Igiri·International Neuropsychiatric Disease Journal·2025
Aim: the aim of this study was to elucidate the effect of alkaloid-rich fraction of Dacryodes edulis on body weight, blood glucose level and the microanatomy of the hippocampus of STZ-induced Diabetic Wistar rats. Methodology: 25 adult male Wistar rats were used for the experimen...
Open access
Research Article10.9734/indj/2025/v22i3477
Background: Carbon soot particulate matter (PM2.5) from crude oil combustion poses significant health risks; however, its systemic and neurological effects remain understudied. This study investigated the impact of chronic carbon soot PM2.5 inhalation on body weight and cerebella...
Open access
Research Article10.9734/indj/2025/v22i3478
Alzheimer's disease is a progressive neurological disorder that primarily affects older adults and is the most common cause of dementia. It involves the degeneration of brain cells, leading to memory loss, cognitive decline, and changes in behavior and personality. Worldwide, an...
Open access
Research Article10.9734/indj/2025/v22i3476
Williams Afamuefuna Nnenna, Ifiok Francis Bassey, Eru Mba Eru, Cyril Abang Agbor, Wilson Okwudili Nnenna, Theresa Ekpenyong Isamoh, Nsikak Michael Umoh, Charles Effiong Asukwo, Emmanuel Izuchukwu Odom & Anozeng Oyono Igiri·International Neuropsychiatric Disease Journal·2025
Introduction: Epilepsy is a chronic neurological disorder characterized by recurrent seizures that severely impact quality of life. The increasing need for safer and more effective anticonvulsant therapies has led to the exploration of herbal remedies. This study investigates the...
Open access
Research Article10.9734/indj/2025/v22i2475
Tramadol hydrochloride (TRM) is widely used for pain management, but chronic exposure can lead to neurotoxicity. Sinapic acid (SA) has been reported to be a potent antioxidant. This study investigates the impacts of SA against TRM-induced oxidative and morphological damage in the...
Open access
Research Article10.9734/indj/2025/v22i2474
Gastrodia elata commonly called Tianmab is a traditional medicinal herb widely used in East Asia for its purported neuroprotective effects. This mini-review summarizes the current understanding of the bioactive compounds within G. elata and their potential mechanisms of action re...
Open access
Research Article10.9734/indj/2025/v22i2473
Background: Industrial effluents contain hazardous contaminants that pose significant risks to environmental and public health, including neurotoxicity. This study aimed to evaluate the histopathological effects of treated and untreated industrial effluents from Notore Chemicals...
Open access
Research Article10.9734/indj/2025/v22i2472
The surge in the prevalence of neurodevelopmental conditions including Autism Spectrum Disorder; a Disarray typically defined by a wide variety of conditions marked by difficulties in social skills, repetitive behaviors, disorganized speech, and challenges with nonverbal communic...
Open access
Research Article10.9734/indj/2025/v22i2471